Walters D V, Olver R E
Pediatr Res. 1978 Mar;12(3):239-42. doi: 10.1203/00006450-197803000-00017.
We have examined the effect on lung liquid secretion of catecholamines infused in chronically catheterized fetal lambs in utero. Isoproterenol and epinephrine inhibited secretion, an effect which increased with gestation and, in fetuses near delivery, caused absorption of lung liquid. In 7 out of 8 experiments nor-epinephrine had no effect on secretion. This pattern of response and the fact that the inhibitory effect could be blocked by propranolol indicate a mode of action involving beta-adrenergic receptors.
我们研究了子宫内长期插管的胎羊输注儿茶酚胺对肺液分泌的影响。异丙肾上腺素和肾上腺素抑制分泌，这种作用随孕周增加而增强，在接近分娩的胎儿中，会导致肺液吸收。在8个实验中的7个，去甲肾上腺素对分泌没有影响。这种反应模式以及普萘洛尔可阻断抑制作用这一事实表明其作用方式涉及β-肾上腺素能受体。
