Zhong Zhi-Ping, Wu Shan-Shan, Liu Bo, You Yu-mei
Department Radiology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jun;30(6):1363-5, 1372.
To investigate the response of the specific brain functional areas of normal human to acupuncture at the acupoints of different Meridians at the same anatomy level.
Twelve healthy young volunteers were enrolled in this research and functional magnetic resonance imaging (fMRI) scans were taken randomly in a block design. During the stimulation phase, an acupuncture needle inserted in right Shenmen (HT7) or Yanglao (SI6) was twirled at an angle of 180 degrees and a frequency of about 1.5 Hz. The collected images were analyzed using SPM2 for exploring the inter-group differences in blood oxygen level dependent (BOLD) responses. RESULTS Increases in BOLD signal (group analysis, corrected, 0.05, K>or=10) were found mainly in the right ostcentral gyrus of the frontal lobe (BA2, BA1, BA43) and left inferior frontal gyrus (BA47) by acupuncture at HT7, and chiefly in the left inferior parietal lobule (BA 40) and right inferior frontal gyrus (BA 45, BA 46) by acupuncture at SI6.
Acupuncture of HT7 and SI6 elicits different BOLD responses in some related cerebral regions correlative with cognition.
探讨正常人同一解剖水平不同经脉穴位针刺时脑特定功能区的反应。
选取12名健康青年志愿者参与本研究，采用组块设计随机进行功能磁共振成像（fMRI）扫描。在刺激阶段，将一根针刺入右侧神门（HT7）或养老（SI6），以180度角、约1.5赫兹的频率捻转。使用SPM2分析采集的图像，以探索血氧水平依赖（BOLD）反应的组间差异。结果针刺HT7时，BOLD信号增强（组分析，校正，0.05，K≥10）主要见于右侧额叶中央前回（BA2、BA1、BA43）和左侧额下回（BA47）；针刺SI6时，主要见于左侧顶下小叶（BA40）和右侧额下回（BA45、BA46）。
针刺HT7和SI6在一些与认知相关的脑区引发不同的BOLD反应。
