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皮肤瘢痕形成:临床综述

Cutaneous scarring: a clinical review.

作者信息

Baker Richard, Urso-Baiarda Fulvio, Linge Claire, Grobbelaar Adriaan

机构信息

Queen Victoria Hospital NHS Foundation Trust, Holtye Road, East Grinstead, West Sussex RH19 3DZ, UK.

出版信息

Dermatol Res Pract. 2009;2009:625376. doi: 10.1155/2009/625376. Epub 2010 Feb 10.

Abstract

Cutaneous scarring can cause patients symptoms ranging from the psychological to physical pain. Although the process of normal scarring is well described the ultimate cause of pathological scarring remains unknown. Similarly, exactly how early gestation fetuses can heal scarlessly remains unsolved. These questions are crucial in the search for a preventative or curative antiscarring agent. Such a discovery would be of enormous medical and commercial importance, not least because it may have application in other tissues. In the clinical context the assessment of scars is becoming more sophisticated and new physical, medical and surgical therapies are being introduced. This review aims to summarise some of the recent developments in scarring research for non-specialists and specialists alike.

摘要

皮肤瘢痕会给患者带来从心理到身体疼痛等一系列症状。尽管正常瘢痕形成的过程已有详尽描述,但病理性瘢痕形成的根本原因仍然未知。同样,妊娠早期胎儿如何实现无瘢痕愈合也尚未得到解答。这些问题对于寻找预防或治疗瘢痕的药物至关重要。这样的发现将具有巨大的医学和商业价值,尤其是因为它可能适用于其他组织。在临床环境中,瘢痕评估正变得越来越精细,新的物理、医学和手术治疗方法也不断涌现。这篇综述旨在为非专业人士和专业人士总结瘢痕研究的一些最新进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87e6/2879602/e18cdd9f0259/DRP2009-625376.001.jpg

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