Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
Vector Borne Zoonotic Dis. 2011 Feb;11(2):103-10. doi: 10.1089/vbz.2009.0071. Epub 2010 Jun 29.
Malaria was common in Romania until largely successful campaigns of the 20th century. Researchers Ioan Cantacuzino, George Zotta, and Mihai Ciuca carried out important early contributions to the understanding of malarial endemo-epidemic situation in Romania. The malarial endemy registered a peak in 1942 with an incidence of 1218 cases per 100,000 inhabitants as a result of the disastrous effects of the Second World War. In the following years the incidence increased from 421.5 cases per 100,000 inhabitants in 1944 to 735.1 cases per 100,000 inhabitants in 1946. A Malaria Commission was formed in February 1947 with the mission to reorganize the fight against malaria in Romania based on international guidelines. Following the adoption of proper malarial eradication methods, namely coverage of endemic areas by spraying of residual insecticides, associated with chemotherapy and, eventually, chemoprophylaxis with synthetic products, and by surveillance, indigenous cases disappeared rapidly, relapsing cases were much reduced, and imported and induced cases remained constant or even increased slightly, probably due to the increase in traffic and in the use of blood transfusions. No indigenous cases have been registered in Romania since 1962. In 1963 the Romanian authorities declared malarial eradication in the territory to the World Health Organization.
疟疾在 20 世纪大规模成功防治运动之前在罗马尼亚很常见。研究者 Ioan Cantacuzino、George Zotta 和 Mihai Ciuca 对了解罗马尼亚疟疾地方流行情况做出了重要的早期贡献。由于第二次世界大战的灾难性影响，1942 年疟疾地方性流行达到高峰，发病率为每 10 万人中有 1218 例。在接下来的几年里，发病率从 1944 年的每 10 万人中有 421.5 例增加到 1946 年的每 10 万人中有 735.1 例。1947 年 2 月成立了疟疾委员会，其任务是根据国际准则重组罗马尼亚的疟疾防治工作。在采用适当的疟疾消除方法后，即通过喷洒残留杀虫剂覆盖流行地区，结合化疗，最终使用合成产品进行化学预防，并通过监测，本地病例迅速消失，复发病例大大减少，输入性病例和诱导性病例保持不变或甚至略有增加，可能是由于交通和输血的增加。自 1962 年以来，罗马尼亚没有登记到本地疟疾病例。1963 年，罗马尼亚当局向世界卫生组织宣布在其领土内消除了疟疾。
