National Emerging Infectious Diseases Laboratories Institute, Boston, Massachusetts 02118, USA.
Emerg Infect Dis. 2010 Jul;16(7):1119-22. doi: 10.3201/eid1607.100159.
Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus-based vaccine is administered 20-30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.
当重组单纯疱疹病毒基于疫苗在感染马尔堡病毒后 20-30 分钟给予时,恒河猴可免受疾病侵害。当这种疫苗在挑战后 24 小时给予时,我们保护了 5/6 的猴子;当疫苗在感染后 48 小时给予时,2/6 的动物受到保护。