Suppr超能文献

患有颈椎脊髓压迫症的患者在遭受轻微创伤后是否会增加颈椎脊髓损伤的风险?

Are subjects with spondylotic cervical cord encroachment at increased risk of cervical spinal cord injury after minor trauma?

机构信息

Department of Neurology, Faculty Hospital and Masaryk University, Jihlavská 20, 625 00 Brno, Czech Republic.

出版信息

J Neurol Neurosurg Psychiatry. 2011 Jul;82(7):779-81. doi: 10.1136/jnnp.2009.198945. Epub 2010 Jun 28.

Abstract

The aim of the study was to analyse the risk of symptomatic myelopathy after minor trauma in patients with asymptomatic spondylotic cervical spinal cord encroachment (ASCCE). In a cohort of 199 patients with ASCCE, previously followed prospectively in a study investigating progression into symptomatic myelopathy, the authors looked retrospectively for traumatic episodes that may have involved injury to the cervical spine. A questionnaire and data file analysis were employed to highlight whatever hypothetical relationship might emerge with the development of symptomatic myelopathy. Fourteen traumatic episodes in the course of a follow-up of 44 months (median) were recorded in our group (who had been instructed to avoid risky activities), with no significant association with the development of symptomatic myelopathy (found in 45 cases). Only three minor traumatic events without fracture of the cervical spine were found among the symptomatic myelopathy cases, with no chronological relationship between trauma and myelopathy. Furthermore, 56 traumatic spinal cord events were found before the diagnosis of cervical cord encroachment was established, with no correlation to either type of compression (discogenic vs osteophytic). In conclusion, the risk of spinal cord injury after minor trauma of the cervical spine in patients with ASCCE appeared to be low in our cohort provided risky activities in these individuals are restricted. Implementation of preventive surgical decompression surgery into clinical practice in these individuals should be postponed until better-designed studies provide proof enough for it to take precedence over a conservative approach.

摘要

本研究旨在分析无症状颈椎脊髓压迫症(ASCCE)患者轻微外伤后症状性脊髓病的风险。在一项前瞻性研究中,作者对 199 例 ASCCE 患者进行了队列研究,以分析无症状性颈椎脊髓压迫症进展为症状性脊髓病的风险,回顾性地寻找可能涉及颈椎损伤的创伤事件。作者采用问卷调查和数据分析的方法,以强调任何可能出现的与症状性脊髓病发展相关的关系。在 44 个月(中位数)的随访过程中,我们的研究组记录了 14 例创伤事件(已告知患者避免危险活动),但与症状性脊髓病的发生无明显相关性(发现 45 例)。在症状性脊髓病病例中,只有 3 例无颈椎骨折的轻微创伤事件,创伤与脊髓病之间无时间关系。此外,在诊断颈椎脊髓压迫之前,发现 56 例脊髓创伤事件,但与椎间盘源性或骨赘源性压迫均无相关性。总之,在我们的研究队列中,ASCCE 患者轻微颈椎外伤后脊髓损伤的风险似乎较低,但前提是限制这些患者的危险活动。在这些患者中,实施预防性减压手术的临床实践应推迟到设计更好的研究提供足够的证据支持手术优于保守治疗。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验