Li Xin, Kao Fu-Jen, Chuang Chien-Chin, He Sailing
Centre for Optical and Electromagnetic Research, State Key Laboratory for Modern Optical Instrumentation, Zhejiang University, Hangzhou, PR China.
Opt Express. 2010 May 24;18(11):11335-46. doi: 10.1364/OE.18.011335.
Nano-composites of quantum dots (QDs) and gold nanorods (GNRs) or silica-coated GNRs (GNRs_SiO2) were synthesized. The attached GNRs modify the excitation intensity and spontaneous emission of QDs through the surface plasmonic effects. The fluorescence from QDs is enhanced and can be optimized by modifying the thickness of silica coated on GNRs, under both one- and two-photon excitations. The measurements of fluorescence intensity and lifetime demonstrate that the enhancement may be attributed to the matching of the localized surface plasmon resonance of GNR to the excitation wavelength. In addition to enhancing QD-fluorescence in QD-GNR@SiO2, GNRs also present as an effective contrast agent for bio-imaging, through light scattering and or two-photon emission, as well as for photo-thermal therapy. The composite's multifunctional characteristics are highly valuable and to be exploited in bio-applications.
合成了量子点（QDs）与金纳米棒（GNRs）或二氧化硅包覆的金纳米棒（GNRs_SiO2）的纳米复合材料。附着的金纳米棒通过表面等离子体效应改变量子点的激发强度和自发发射。在单光子和双光子激发下，量子点的荧光都会增强，并且可以通过改变包覆在金纳米棒上的二氧化硅的厚度来优化。荧光强度和寿命的测量表明，这种增强可能归因于金纳米棒的局域表面等离子体共振与激发波长的匹配。除了增强QD-GNR@SiO2中量子点的荧光外，金纳米棒还通过光散射和/或双光子发射作为生物成像的有效造影剂，以及用于光热治疗。该复合材料的多功能特性在生物应用中具有很高的价值，有待开发利用。
