Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, China.
Nanoscale. 2011 Apr;3(4):1756-9. doi: 10.1039/c0nr00863j. Epub 2011 Feb 18.
This article describes a nonaggregation-based colorimetric assay of ascorbic acid by tailoring the optical properties of mesoporous silica-coated gold nanorods (MS GNRs) via silver overcoating. The colorimetric measurement of ascorbic acid (AA) concentration strongly relies on the fact that the blue shift effect of localized surface plasmon resonance (LSPR) peak of MS GNRs is gradually enlarged with the increase of AA amount. The limit of detection is determined to be 49 nM, which is comparable to that of quantum dots (QDs)-based fluorimetric methods.
本文通过在介孔硅包裹的金纳米棒（MS GNRs）表面覆盖银层，来修饰其光学性质，从而实现基于非聚集的抗坏血酸比色分析。通过银覆盖层来逐渐增大 MS GNRs 的局域表面等离子体共振（LSPR）峰的蓝移效应，实现对 AA 浓度的比色测量。检测限被确定为 49 nM，与基于量子点（QDs）的荧光法相当。
