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[Regulatory mechanism of HTLV-1 replication and its association with abnormal cell growth].[人类嗜T淋巴细胞病毒1型(HTLV-1)复制的调控机制及其与细胞异常生长的关联]
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Genome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30.对受人类嗜T淋巴细胞病毒I型(HTLV-I)蛋白p30转录调控和转录后调控的人类基因进行全基因组分析。
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p30 protein: a critical regulator of HTLV-1 viral latency and host immunity.p30 蛋白:HTLV-1 病毒潜伏期和宿主免疫的关键调节因子。
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Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.c-MYC癌蛋白的乙酰化是其与HTLV-1 p30(II)辅助蛋白协同作用以及由p30(II)/c-MYC诱导致癌性细胞转化所必需的。
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HTLV-1 and HTLV-2: highly similar viruses with distinct oncogenic properties.人类嗜 T 淋巴细胞病毒 1 型和 2 型:高度相似但具有不同致癌特性的病毒。
Front Microbiol. 2014 Jul 29;5:398. doi: 10.3389/fmicb.2014.00398. eCollection 2014.
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Cell cycle regulation during viral infection.病毒感染期间的细胞周期调控。
Methods Mol Biol. 2014;1170:165-227. doi: 10.1007/978-1-4939-0888-2_10.
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Overview on HTLV-1 p12, p8, p30, p13: accomplices in persistent infection and viral pathogenesis.HTLV-1 p12、p8、p30、p13 概述:持续性感染和病毒发病机制中的共犯。
Front Microbiol. 2012 Dec 11;3:400. doi: 10.3389/fmicb.2012.00400. eCollection 2012.
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Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV-1 and HTLV-2.人类嗜T淋巴细胞病毒1型(HTLV-1)与人类嗜T淋巴细胞病毒2型(HTLV-2)的基因组织、表达策略及致癌潜力比较
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本文引用的文献

1
Genome wide analysis of human genes transcriptionally and post-transcriptionally regulated by the HTLV-I protein p30.对受人类嗜T淋巴细胞病毒I型(HTLV-I)蛋白p30转录调控和转录后调控的人类基因进行全基因组分析。
BMC Genomics. 2009 Jul 14;10:311. doi: 10.1186/1471-2164-10-311.
2
Deregulation of microRNA involved in hematopoiesis and the immune response in HTLV-I adult T-cell leukemia.人嗜T淋巴细胞病毒I型成人T细胞白血病中参与造血和免疫反应的微小RNA失调
Blood. 2009 May 14;113(20):4914-7. doi: 10.1182/blood-2008-11-189845. Epub 2009 Feb 26.
3
Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo.人类2型T细胞白血病病毒转录后调控蛋白p28是病毒在体内感染性和持续性所必需的。
Retrovirology. 2008 May 12;5:38. doi: 10.1186/1742-4690-5-38.
4
Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival.人类嗜T淋巴细胞病毒1型p30改变T淋巴细胞的细胞周期G2调控以提高细胞存活率。
Retrovirology. 2007 Jul 16;4:49. doi: 10.1186/1742-4690-4-49.
5
Human T-cell lymphotrophic virus type I rex and p30 interactions govern the switch between virus latency and replication.人类I型嗜T细胞淋巴细胞病毒的rex蛋白与p30蛋白的相互作用决定了病毒潜伏与复制之间的转换。
J Biol Chem. 2007 May 11;282(19):14608-15. doi: 10.1074/jbc.M611219200. Epub 2007 Mar 14.
6
Human T-cell leukemia virus type I p30 nuclear/nucleolar retention is mediated through interactions with RNA and a constituent of the 60 S ribosomal subunit.人类I型T细胞白血病病毒p30的核/核仁滞留是通过与RNA和60S核糖体亚基的一个组成成分相互作用介导的。
J Biol Chem. 2006 Dec 1;281(48):37150-8. doi: 10.1074/jbc.M603981200. Epub 2006 Sep 28.
7
Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activity.p300的组蛋白乙酰转移酶(HAT)活性调节1型人类嗜T淋巴细胞病毒p30II介导的LTR转录活性抑制。
Virology. 2006 Oct 25;354(2):225-39. doi: 10.1016/j.virol.2006.07.002. Epub 2006 Aug 4.
8
The HTLV-I p30 interferes with TLR4 signaling and modulates the release of pro- and anti-inflammatory cytokines from human macrophages.人嗜T淋巴细胞病毒I型p30干扰Toll样受体4信号传导,并调节人巨噬细胞促炎和抗炎细胞因子的释放。
J Biol Chem. 2006 Aug 18;281(33):23414-24. doi: 10.1074/jbc.M600684200. Epub 2006 Jun 19.
9
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.编码PU.1的基因的一个关键调控元件可抑制淋巴细胞的生长和转化。
Nat Genet. 2006 Jan;38(1):27-37. doi: 10.1038/ng1679. Epub 2005 Nov 27.
10
Human T-cell leukemia/lymphoma virus type 1 nonstructural genes and their functions.人类T细胞白血病/淋巴瘤病毒1型非结构基因及其功能。
Oncogene. 2005 Sep 5;24(39):6026-34. doi: 10.1038/sj.onc.1208977.

HTLV-I p30: a versatile protein modulating virus replication and pathogenesis.

作者信息

Bai Xue Tao, Baydoun Hicham Hachem, Nicot Christophe

机构信息

University of Kansas Medical Center, Department of Pathology and Laboratory Medicine, Kansas City, KS 66160, USA.

出版信息

Mol Aspects Med. 2010 Oct;31(5):344-9. doi: 10.1016/j.mam.2010.05.004. Epub 2010 Jun 4.

DOI:10.1016/j.mam.2010.05.004
PMID:20595036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2981346/
Abstract
摘要