Fong Farina, Odell Edward, Simo Ricard
Department of Otorhinolaryngology, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Head Neck Pathol. 2009 Mar;3(1):47-50. doi: 10.1007/s12105-008-0098-6. Epub 2008 Dec 10.
Collagenous fibromas are rare fibrous soft tissue tumours that usually arise in subcutaneous tissue or skeletal muscle at a variety of anatomical sites. These lesions commonly present as painless, slow-growing mobile masses. We describe a unique case of a 41-year-old woman presenting with a posterior neck swelling and longstanding history of severe ongoing pain in the right scapular region, shoulder and neck, weakness of the palmar grip and limited right lateral neck flexion and rotation. A history of trauma to the right neck in adolescence was noted. Histological analysis revealed a paucicellular lesion with spindle and stellate-shaped fibroblasts involving the cervical nerve roots, typical of collagenous fibroma. In a literature search on Medline and Pubmed, we found no reported cases of collagenous fibromas presenting with neurological symptoms. This report highlights the potential of these lesions to present with neurological symptoms due to infiltration of surrounding tissues, and that preceding trauma may contribute to the aetiology.
胶原纤维瘤是一种罕见的纤维性软组织肿瘤，通常发生于皮下组织或骨骼肌的各种解剖部位。这些病变通常表现为无痛、生长缓慢的可移动肿块。我们描述了一例独特的病例，一名41岁女性，出现后颈部肿胀，并有右肩胛区、肩部和颈部长期严重持续疼痛、掌部握力减弱以及右侧颈部侧屈和旋转受限的病史。注意到其在青春期有右颈部外伤史。组织学分析显示为一个细胞稀少的病变，有梭形和星状成纤维细胞累及颈神经根，这是胶原纤维瘤的典型表现。在对Medline和Pubmed进行文献检索时，我们未发现有报道胶原纤维瘤出现神经症状的病例。本报告强调了这些病变因周围组织浸润而出现神经症状的可能性，以及既往创伤可能在病因学中起作用。
