Microb Cell Fact. 2010 Jul 5;9:53. doi: 10.1186/1475-2859-9-53.
Nanotechnology is increasingly using both materials and nano-objects synthesized by living beings, most of them produced by microbial cells. Emerging technologies and highly integrative approaches (such as 'omics and systems biology), that have been largely proven successful for the production of proteins and secondary metabolites are now expected to become fully adapted for the improved biological production of nanostructured materials with tailored properties. The so far underestimated potential of microbial cell factories in nanotechnology and nanomedicine is expected to emerge, in the next years, in the context of novel needs envisaged in the nanoscience universe. This should prompt a careful revisiting of the microbial cell factories as the most versatile biological platforms to supply functional materials for nanotechnological applications.
纳米技术越来越多地使用由生物体合成的材料和纳米物体,其中大多数是由微生物细胞产生的。新兴技术和高度综合的方法(如“组学”和系统生物学)已经在蛋白质和次生代谢物的生产中被证明是非常成功的,现在预计将完全适应于具有定制特性的纳米结构材料的生物生产的改进。在纳米科学领域,预计微生物细胞工厂在纳米技术和纳米医学方面的潜力,在未来几年内,将随着新的需求而显现出来。这应该促使人们重新审视微生物细胞工厂作为供应用于纳米技术应用的功能材料的最通用的生物平台。