Héritier F, Perret C, Fitting J W
Service des Soins Intensifs, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Chest. 1991 Jul;100(1):175-8. doi: 10.1378/chest.100.1.175.
Inspiratory muscle strength most often is better reflected by sniff Pes than PImax against occlusion. Furthermore, sniff Pes can be estimated noninvasively by the measurement of sniff Pmo in normal subjects and in patients with respiratory muscle weakness. The aim of this study was to compare sniff Pmo and P.PImax to assess inspiratory muscle strength in patients with acute respiratory failure. The highest pressure was produced by P.PImax in 61 percent of measurements, and by sniff Pmo in 39 percent. Above 35 cm H2O P.PImax yielded the highest pressure in 55 percent of cases and the ratio sniff Pmo/P.PImax was 1.20 +/- 0.54. Below 35 cm H2O, P.PImax yielded the highest pressure in 75 percent of cases and the ratio sniff Pmo/P.PImax was 0.76 +/- 0.35 (p less than 0.02). Thus, measurements of sniff Pmo and P.PImax complement one another for assessing inspiratory muscle strength. However, sniff Pmo underestimates inspiratory muscle strength in patients with severe inspiratory muscle weakness.
与对抗阻塞时的最大吸气压（PImax）相比，吸气肌力量通常通过吸气鼻腔压力（sniff Pes）能得到更好的反映。此外，在正常受试者和呼吸肌无力患者中，可通过测量吸气口腔压力（sniff Pmo）来无创估计sniff Pes。本研究的目的是比较sniff Pmo和P.PImax，以评估急性呼吸衰竭患者的吸气肌力量。在61%的测量中，P.PImax产生的压力最高，39%的测量中sniff Pmo产生的压力最高。在35 cm H2O以上，55%的病例中P.PImax产生的压力最高，sniff Pmo/P.PImax的比值为1.20±0.54。在35 cm H2O以下，75%的病例中P.PImax产生的压力最高，sniff Pmo/P.PImax的比值为0.76±0.35（p<0.02）。因此，sniff Pmo和P.PImax的测量在评估吸气肌力量方面相互补充。然而，sniff Pmo会低估严重吸气肌无力患者的吸气肌力量。
