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儿童补充医学的证据基础:系统评价的批判性概述。

The evidence-base for complementary medicine in children: a critical overview of systematic reviews.

机构信息

Complementary Medicine, Peninsula Medical School, University of Exeter, 25 Victoria Park Road, Exeter EX2 4NT, UK.

出版信息

Arch Dis Child. 2011 Aug;96(8):769-76. doi: 10.1136/adc.2009.179036. Epub 2010 Jul 6.

Abstract

BACKGROUND

The use of complementary and alternative medicine (CAM) in paediatric populations is common yet, to date, there has been no synthesis of the evidence of its effectiveness in that population. This overview of systematic review evaluates the evidence for or against the effectiveness of CAM for any childhood condition.

METHODS

Medline, AMED and Cochrane were searched from inception until September 2009. Reference lists of retrieved articles were hand-searched. Experts in the field of CAM were contacted. No language restrictions were applied.

RESULTS

17 systematic reviews were included in this overview, covering acupuncture, chiropractic, herbal medicine, homeopathy, hypnotherapy, massage and yoga. Results were unconvincing for most conditions although there is some evidence to suggest that acupuncture may be effective for postoperative nausea and vomiting, and that hypnotherapy may be effective in reducing procedure-related pain. Most of the reviews failed to mention the incidence of adverse effects of CAMs.

CONCLUSIONS

Although there is some encouraging evidence for hypnosis, herbal medicine and acupuncture, there is insufficient evidence to suggest that other CAMs are effective for the treatment of childhood conditions. Many of the systematic reviews included in this overview were of low quality, as were the randomised clinical trials within those reviews, further reducing the weight of that evidence. Future research in CAM for children should conform to the reporting standards outlined in the CONSORT and PRISMA guidelines.

摘要

背景

在儿科人群中使用补充和替代医学(CAM)很常见,但迄今为止,尚无关于其在该人群中有效性的证据综合。本次系统评价综述评估了 CAM 对任何儿童疾病的有效性的证据。

方法

从建库到 2009 年 9 月,检索了 Medline、AMED 和 Cochrane。手工检索检索到的文章的参考文献列表。联系了 CAM 领域的专家。未应用语言限制。

结果

本次综述共纳入 17 项系统评价,涵盖针灸、整脊、草药、顺势疗法、催眠疗法、按摩和瑜伽。尽管有一些证据表明针灸可能对术后恶心和呕吐有效,催眠疗法可能对减少与手术相关的疼痛有效,但对于大多数疾病,结果并不令人信服。大多数综述都没有提到 CAM 的不良反应发生率。

结论

尽管催眠、草药和针灸有一些令人鼓舞的证据,但没有足够的证据表明其他 CAM 对儿童疾病的治疗有效。本次综述中纳入的许多系统评价质量较低,其中的随机临床试验也较低,进一步降低了该证据的权重。未来针对儿童的 CAM 研究应符合 CONSORT 和 PRISMA 指南中概述的报告标准。

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