Division of Geriatrics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Ann Epidemiol. 2010 Aug;20(8):617-28. doi: 10.1016/j.annepidem.2010.05.003.
To quantify socioeconomic status and ethnic differences in risk for coronary heart disease (CHD) accrued from major risk factors in the United States.
Data came from the National Health and Nutrition Examination Survey 2001-2006. Outcomes examined were (a) 10-year risk for CHD events as predicted by the National Cholesterol Education Program Adult Treatment Panel III 2004 Updated Guidelines; and (b) the prevalence of the metabolic syndrome and overt diabetes mellitus (a CHD risk-equivalent).
Strong inverse socioeconomic gradients with risk were present in all race/ethnicity groups except foreign-born Mexican American men, and were attenuated by controls for physical activity, smoking, and abdominal obesity. In contrast, race/ethnicity disparities were seen in some but not all socioeconomic strata, with some non-Hispanic Blacks and US-born Mexican Americans having higher risk and some foreign-born Mexican Americans having lower risk.
Disparities in cardiovascular risk in the United States are primarily related to socioeconomic status and less to race/ethnicity. Socioeconomically disadvantaged individuals should be targeted for lifestyle counseling and early screening for risk factors, regardless of race/ethnicity, to reduce social disparities in cardiovascular outcomes.
定量分析美国主要危险因素导致的冠心病(CHD)风险的社会经济地位和种族差异。
数据来自 2001-2006 年的全国健康和营养检查调查。所检查的结果是:(a) 经国家胆固醇教育计划成人治疗小组第三版 2004 年更新指南预测的 10 年 CHD 事件风险;(b) 代谢综合征和显性糖尿病(CHD 等效风险)的患病率。
除了出生在国外的墨西哥裔美国男性外,所有种族/民族群体中都存在与风险呈强烈反比的社会经济梯度,并且通过控制身体活动、吸烟和腹部肥胖等因素,这些梯度有所减弱。相比之下,在某些但不是所有社会经济阶层中都存在种族/民族差异,一些非西班牙裔黑人和出生在美国的墨西哥裔美国人的风险较高,而一些出生在国外的墨西哥裔美国人的风险较低。
美国心血管风险的差异主要与社会经济地位有关,与种族/民族关系较小。无论种族/民族如何,社会经济地位处于不利地位的个人都应该成为生活方式咨询和早期风险因素筛查的目标,以减少心血管结果的社会差异。