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接触大鼠后不明原因发热:鼠咬热或哈弗希尔热

[Unexplained fever after exposure to rats: rat bite fever or Haverhill fever].

作者信息

Hurkens Kim P G M, Pijpers Evelien, Stehouwer Coen D A

机构信息

Maastricht University Medical Centre, afd. Algemene Interne Geneeskunde, Maastricht, the Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2010;154:A1365.

Abstract

A 24-year old man presented himself to the emergency ward with complaints of fever, nausea, headache, muscle ache and chest pain. Two weeks before presentation he had been bitten by a pet rat. We determined that he had bacteraemia caused by a Streptobacillus moniliformis infection, which led to the development of an illness called rat bite fever. S. moniliformis is a pleomorphic gram-negative rod-shaped bacterium that is considered part of the normal nasopharyngeal flora in rats. It is the cause of two similar illnesses: rat bite fever and Haverhill fever. Clinicians should consider these infections in the work-up of unexplained fever or sepsis, certainly in the presence of known exposure to rats. Treatment consists of antibiotics.

摘要

一名24岁男子因发热、恶心、头痛、肌肉疼痛和胸痛前往急诊病房就诊。就诊前两周,他被一只宠物鼠咬伤。我们确定他患有由念珠状链杆菌感染引起的菌血症,这导致了一种名为鼠咬热的疾病的发展。念珠状链杆菌是一种多形性革兰氏阴性杆状细菌,被认为是大鼠正常鼻咽菌群的一部分。它是两种类似疾病的病因:鼠咬热和哈弗希尔热。临床医生在对不明原因发热或败血症进行检查时应考虑这些感染,尤其是在已知有接触大鼠的情况下。治疗包括使用抗生素。

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