Pediatric Dermatology Department, San Gallicano Institute, Istituti Fisioterapici Ospitalieri, Rome, Italy.
J Am Acad Dermatol. 2010 Nov;63(5):782-8. doi: 10.1016/j.jaad.2009.11.021. Epub 2010 Jul 8.
Postadolescent acne is usually described as an inflammatory, mild-to-moderate dermatosis, frequently involving the lower third of the face, the jawline, and the neck. However, we have also frequently observed a clinical form predominantly characterized by retention lesions (microcomedones and macrocomedones), with few inflammatory lesions (comedonal postadolescent acne [CPAA]), which appears significantly correlated with cigarette smoking.
We sought to investigate the clinical features of postadolescent acne in a group of female patients affected by acne and its relationship with cigarette smoking.
A total of 226 women with acne (25-50 years) attending our department were examined by a team of 3 dermatologists, to assess the age of onset of the disease, and the number, type, and distribution of acne lesions.
In all, 192 of 226 patients (85.0%) were classified as having CPAA and 34 as having papulopustular postadolescent acne. A smoking habit was confirmed in 150 of 226 (66.3%). Remarkably, 72.9% of patients with CPAA were smokers as compared with only 29.4% of those with papulopustular postadolescent acne (P < .0001).
Possible limitations are related to geographic area or to the prevalence of darker skin types (III and IV) (data about skin types have not been collected). Other possible aggravating factors (ie, stress and diet) have not been investigated.
According to our results, CPAA appears as the most frequent clinical form of postadolescent acne and seems to be strictly correlated with cigarette smoking.
青春期后痤疮通常被描述为一种炎症性、轻至中度皮肤病，常累及面下部、下颌线和颈部。然而，我们也经常观察到一种以潴留性皮损（微粉刺和大粉刺）为主，炎症性皮损较少的临床形式（粉刺性青春期后痤疮[CPAA]），这种形式与吸烟显著相关。
我们旨在研究一组患有痤疮的女性患者的青春期后痤疮的临床特征及其与吸烟的关系。
我们的皮肤科医生团队对 226 名（25-50 岁）患有痤疮的女性患者进行了检查，以评估疾病的发病年龄、痤疮皮损的数量、类型和分布。
在 226 名患者中，192 名（85.0%）被归类为 CPAA，34 名被归类为丘疹脓疱性青春期后痤疮。在 226 名患者中，150 名（66.3%）有吸烟史。值得注意的是，CPAA 患者中吸烟者占 72.9%，而丘疹脓疱性青春期后痤疮患者中吸烟者仅占 29.4%（P<0.0001）。
可能的局限性与地理区域或较深肤色类型（III 型和 IV 型）的流行率有关（未收集关于皮肤类型的数据）。其他可能的加重因素（如压力和饮食）尚未得到调查。
根据我们的结果，CPAA 似乎是青春期后痤疮最常见的临床形式，与吸烟密切相关。
