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花生口服免疫治疗尚未准备好用于临床。

Peanut oral immunotherapy is not ready for clinical use.

出版信息

J Allergy Clin Immunol. 2010 Jul;126(1):31-2. doi: 10.1016/j.jaci.2010.05.012.

Abstract

Peanut OIT has shown promise as a potential treatment for food allergy. However, there remain numerous unanswered questions surrounding this investigational treatment, including the risks of OIT compared to avoidance, dosing regimen issues, patient selection, post-desensitization strategy, allocation of clinical resources, and reimbursement. Further studies are needed to address these outstanding issues in order to determine if this type of therapy is appropriate for clinical use.

摘要

花生 OIT 已显示出作为一种潜在的食物过敏治疗方法的前景。然而,围绕这种试验性治疗仍有许多未解决的问题,包括与回避相比 OIT 的风险、剂量方案问题、患者选择、脱敏后策略、临床资源分配和报销等。需要进一步的研究来解决这些悬而未决的问题,以确定这种治疗类型是否适合临床应用。

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本文引用的文献

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Oral peanut immunotherapy in children with peanut anaphylaxis.儿童花生过敏的口服花生免疫治疗。
J Allergy Clin Immunol. 2010 Jul;126(1):83-91.e1. doi: 10.1016/j.jaci.2010.04.030. Epub 2010 Jun 12.
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Food allergy among children in the United States.美国儿童中的食物过敏情况。
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Clinical efficacy and immune regulation with peanut oral immunotherapy.花生口服免疫疗法的临床疗效与免疫调节
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Safety of a peanut oral immunotherapy protocol in children with peanut allergy.花生过敏儿童的花生口服免疫疗法方案的安全性。
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Oral immunotherapy for food allergy.食物过敏的口服免疫疗法。
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Successful oral tolerance induction in severe peanut allergy.在严重花生过敏中成功诱导口服耐受。
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