Division of Endocriniology, Ohio State University, Columbus, OH, USA.
Clin Oncol (R Coll Radiol). 2010 Aug;22(6):395-404. doi: 10.1016/j.clon.2010.05.004. Epub 2010 Jun 3.
Thyroid cancer comprises a broad spectrum of diseases with variable prognoses. Although most patients with this disease have excellent overall survival, there are some who do not fare so well. With the worldwide increase in incidence, the need to identify which tumours pose the greatest risk to patients is more acute than ever. This paper will discuss this rising trend in incidence with an analysis of the possible reasons for the increase. In addition, the paper will explore the factors that portend a worse prognosis for the individual patient. Finally, the limitations of the current staging systems will be discussed, with particular emphasis on why they are not as informative in the management of patients with thyroid cancer.
甲状腺癌包括一系列预后不同的疾病。尽管大多数甲状腺癌患者的整体生存率良好，但也有部分患者预后不佳。随着全球发病率的上升，确定哪些肿瘤对患者的风险最大比以往任何时候都更加紧迫。本文将讨论发病率的上升趋势，并分析发病率上升的可能原因。此外，本文还将探讨预示患者预后较差的因素。最后，将讨论当前分期系统的局限性，特别强调其在甲状腺癌患者管理中的信息性不足的原因。
