Ralph H. Johnson V.A. Medical Center and Department of Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
J Womens Health (Larchmt). 2010 Aug;19(8):1449-58. doi: 10.1089/jwh.2009.1652.
Studies of weight and health-related quality of life (HRQOL) generally focus on white populations. This analysis examines the association between clinical weight categories and physical HRQOL in five racial/ethnic groups of older women and determines the extent to which emotional/psychological (social support, caregiver burden) and physical health (diabetes, osteoarthritis) factors modify this relationship.
The cross-sectional analysis, completed in 2007, used baseline data from postmenopausal women enrolled in the Women's Health Initiative (WHI) during the 5-year recruitment period (1993-1998).
Of 161,393 women, 83% were non-Hispanic white, 9% were African American, 4% were Hispanic/Latina, 3% were Asian/Pacific Islander, and <1% were American Indian/Alaska Native. Obesity (body mass index [BMI] > or =30 kg/m(2)) was most common in non-Asian minority groups. Regression modeling showed higher odds of poor physical HRQOL with increasing weight category in all groups. In the total sample, these odds were at least 6 times as high in women with class 3 obesity as in women of normal weight and were only mildly attenuated after the analysis adjusted for emotional/psychological factors. Further adjustment for physical health factors made odds ratio (OR) estimates drop from 2.36 to 1.59 for class 1 obesity and from 6.96 to 3.71 for class 3 obesity. This pattern generally persisted within each racial/ethnic group.
Heavier weight negatively affects physical HRQOL in postmenopausal women across diverse racial/ethnic backgrounds. Weight-relevant physical health factors have a greater impact on this weight-HRQOL association than do emotional/psychological factors.
研究体重与健康相关生活质量（HRQOL）通常集中在白人群体。本分析研究了五种不同种族/族裔的老年女性的临床体重类别与身体 HRQOL 之间的关联，并确定了情绪/心理（社会支持、照顾者负担）和身体健康（糖尿病、骨关节炎）因素在多大程度上改变了这种关系。
横断面分析于 2007 年完成，使用了参加妇女健康倡议（WHI）的绝经后妇女在 5 年招募期间（1993-1998 年）的基线数据。
在 161393 名女性中，83%是非西班牙裔白人，9%是非裔美国人，4%是西班牙裔/拉丁裔，3%是亚洲/太平洋岛民，不到 1%是美洲印第安人/阿拉斯加原住民。肥胖（身体质量指数[BMI]≥30kg/m2）在非亚裔少数群体中最为常见。回归模型显示，在所有组中，体重类别增加与较差的身体 HRQOL 相关的几率更高。在总样本中，与体重正常的女性相比，体重 3 级肥胖的女性身体 HRQOL 较差的几率至少高 6 倍，并且在分析中调整了情绪/心理因素后，这种几率仅略有降低。进一步调整身体健康因素使肥胖 1 级的比值比（OR）估计值从 2.36 降至 1.59，肥胖 3 级的 OR 估计值从 6.96 降至 3.71。这种模式在每个种族/族裔群体中基本保持一致。
在不同种族/族裔背景的绝经后女性中，体重越重，对身体 HRQOL 的负面影响越大。与体重相关的身体健康因素对体重与 HRQOL 之间的关联影响大于情绪/心理因素。
