Research Section of Mental Health Epidemiology, Department of Health Promotion and Development, Faculty of Psychology, University of Bergen, Bergen, Norway.
J Psychosom Res. 2010 Jul;69(1):59-67. doi: 10.1016/j.jpsychores.2010.03.007. Epub 2010 May 4.
Rates of disability pension (DP) awards remain high in most developed countries. We aimed to estimate the impact of anxiety and depression on DPs awarded both for mental and for physical diagnoses and to estimate the relative contribution of sub case-level anxiety and depression compared with case-level symptom loads.
Information from a large cohort study on mental and physical health in individuals aged 40-46 (N=15,288) was linked to a comprehensive national database of disability benefits. Case-level and sub case-level anxiety and depression were defined as scores on the Hospital Anxiety and Depression Scale of >or=8 and 5-7, respectively. The outcome was incident award of a DP (including ICD-10 diagnosis) during 1-7-year follow-up.
DP awards for all diagnoses were predicted both from case-level anxiety [HR 1.90 (95% CI 1.50-2.41)], case-level depression [HR 2.44 (95% CI 1.65-3.59] and comorbid anxiety and depression [HR 4.92 (95% CI 3.94-6.15)] at baseline. These effects were only partly accounted for by adjusting for baseline somatic symptoms and diagnoses. Anxiety and depression also predicted awards for physical diagnoses [HR 3.26 (95% CI 2.46-4.32)]. The population attributable fractions (PAF) of sub case-level anxiety and depression symptom loads were comparable to those from case-level symptom loads (PAF anxiety 0.07 versus 0.11, PAF depression 0.05 versus 0.06).
The long-term occupational impact of symptoms of anxiety and depression is currently being underestimated. Sub case-level symptom loads of anxiety and depression make an important and previously unmeasured contribution to DP awards.
在大多数发达国家,残疾抚恤金(DP)的发放率仍然很高。我们旨在评估焦虑和抑郁对精神和身体诊断的 DP 发放的影响,并评估亚病例水平的焦虑和抑郁与病例水平的症状负荷相比的相对贡献。
一项关于 40-46 岁人群心理健康和身体健康的大型队列研究(N=15288)的信息与一个全面的国家残疾福利数据库相关联。病例水平和亚病例水平的焦虑和抑郁分别定义为医院焦虑和抑郁量表得分>8 和 5-7。结局是在 1-7 年的随访期间初次获得 DP 奖励(包括 ICD-10 诊断)。
所有诊断的 DP 奖励都与基线时的病例水平焦虑[HR 1.90(95%CI 1.50-2.41)]、病例水平抑郁[HR 2.44(95%CI 1.65-3.59]和共病焦虑和抑郁[HR 4.92(95%CI 3.94-6.15)]相关。通过调整基线躯体症状和诊断,这些影响仅部分得到解释。焦虑和抑郁也预测了身体诊断的奖励[HR 3.26(95%CI 2.46-4.32)]。亚病例水平的焦虑和抑郁症状负荷的人群归因分数(PAF)与病例水平的症状负荷相当(PAF 焦虑 0.07 对 0.11,PAF 抑郁 0.05 对 0.06)。
目前,症状性焦虑和抑郁的长期职业影响被低估了。亚病例水平的焦虑和抑郁症状负荷对 DP 奖励有重要的、以前未被测量的贡献。