Mishkin S, Bates J, O'Hashi J, Schneider P, Sniderman A D, Wolf R O
Can Med Assoc J. 1976 Nov 20;115(10):1016-9.
Lipemic serum from three patients with acute pancreatitis and type IV hyperlipemia was fractionated into very-low-density lipoproteins and clear serum. Amylase activity (determined by the Phadebas method) in the component fractions did not exceed that in the original lipemic serum. Addition of these fractions or VLDL and chylomicrons from asymptomatic patients with hyperlipemia to nonlipemic serum from patients with "routine acute pancreatitis" did not inhibit amylase activity or alter the electrophoretic mobility of amylase isoenzymes. Therefore the normal amylase activity often observed in hyperlipemic pancreatitis does not result from an inhibition of amylase activity by serum lipoproteins.
从三名患有急性胰腺炎和IV型高脂血症的患者中获取的脂血血清被分离成极低密度脂蛋白和澄清血清。各组分中的淀粉酶活性（通过法德巴斯法测定）不超过原始脂血血清中的活性。将这些组分或来自无症状高脂血症患者的极低密度脂蛋白和乳糜微粒添加到“常规急性胰腺炎”患者的非脂血血清中，不会抑制淀粉酶活性，也不会改变淀粉酶同工酶的电泳迁移率。因此，高脂血症性胰腺炎中经常观察到的正常淀粉酶活性并非由血清脂蛋白对淀粉酶活性的抑制所致。
