Dipartimento di Scienze Neurologiche, Università degli Studi di Milano, Centro Clinico per le Neuronanotecnologie e la Neurostimolazione, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milano, Italy.
Brain Stimul. 2009 Oct;2(4):241-5. doi: 10.1016/j.brs.2009.02.004. Epub 2009 Apr 3.
In recent years two techniques have become available to stimulate the human brain noninvasively through the scalp: repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS). Prolonged application of either method (eg, several hundred TMS pulses [rTMS] or several minutes of tDCS) leads to changes in excitability of the cortex that outlast the period of stimulation. Because of this, besides the implications for experimental neuroscientists, there is increasing interest in the potential for applying either method as a therapy in neurology, psychiatry, rehabilitation, and pain. Given that both techniques lead to the same final result, this article discusses in theory several issues that can help an investigator to decide whether rTMS or tDCS would be more suitable for the scope of the planned work.
近年来，有两种技术可通过头皮非侵入性地刺激人脑：重复经颅磁刺激（rTMS）和经颅直流电刺激（tDCS）。这两种方法的长时间应用（例如，数百个 TMS 脉冲[rTMS]或几分钟的 tDCS）会导致皮层兴奋性的变化，这种变化会持续超过刺激期。由于这个原因，除了对实验神经科学家的意义之外，人们对将这两种方法作为神经病学、精神病学、康复和疼痛治疗的潜在方法越来越感兴趣。鉴于这两种技术都能达到相同的最终结果，本文从理论上讨论了一些可以帮助研究人员决定 rTMS 或 tDCS 更适合计划工作范围的问题。
