美沙酮维持治疗与心理社会门诊治疗的男性：一项多地点艾滋病毒预防干预试验中，性行为风险行为和干预效果的差异。
Men in methadone maintenance versus psychosocial outpatient treatment: differences in sexual risk behaviors and intervention effectiveness from a multisite HIV prevention intervention trial.
机构信息
University of Washington Alcohol and Drug Abuse Institute, Seattle, WA 98105, USA.
出版信息
J Addict Dis. 2010 Jul;29(3):370-82. doi: 10.1080/10550887.2010.489451.
Abstract
The effectiveness of the Real Men Are Safe (REMAS) HIV prevention intervention was examined as a function of treatment program modality. REMAS was associated with significantly larger decreases in unprotected sexual occasions than an HIV education control condition in both treatment modalities. REMAS had superior effectiveness for reducing unprotected sexual occasions in the psychosocial outpatient compared to methadone. At the 6-month follow-up, the adjusted mean change for REMAS completers in psychosocial outpatient (M=6.4, d=0.38) was greater than for REMAS completers in methadone programs (M=2.3, d=0.25). Reasons for why REMAS appears to be especially effective in psychosocial outpatient programs are explored.
摘要
该研究旨在探讨真实男人安全（REMAS）艾滋病毒预防干预措施的有效性是否取决于治疗方案模式。结果表明，与艾滋病教育对照组相比，无论采用何种治疗模式，REMAS 均可显著降低无保护性行为的发生次数。与美沙酮治疗相比，在心理社会门诊治疗中，REMAS 对于减少无保护性行为具有更显著的效果。在 6 个月的随访中，心理社会门诊治疗中 REMAS 完成者的调整后平均变化（M=6.4，d=0.38）大于美沙酮治疗中 REMAS 完成者的变化（M=2.3，d=0.25）。本文探讨了 REMAS 在心理社会门诊治疗中特别有效的原因。
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