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癌症患者的神经性疼痛——在印度城市一家三级保健麻醉转诊诊所的患病率和管理。

Neuropathic pain in cancer patients--prevalence and management in a tertiary care anesthesia-run referral clinic based in urban India.

机构信息

Department of Anaesthesia, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Palliat Med. 2010 Jul;13(7):819-24. doi: 10.1089/jpm.2009.0405.

Abstract

BACKGROUND

Cancer pain is often intractable and has a considerable impact on the quality of life. Nociceptive pain is easily recognized and managed using conventional analgesics. The neuropathic component makes cancer pain difficult to manage. The epidemiology of neuropathic pain in cancer patients has not been well documented.

AIM OF THE STUDY

This retrospective study attempted to discern the prevalence of neuropathic pain over a period of 2 years, in cancer patients at the Pain and Palliative Care Clinic of a tertiary care cancer center in India. The study also aimed to describe the approach to neuropathic cancer pain alleviation.

MATERIALS AND METHODS

A retrospective analysis of 3238 cancer patients who presented with complaints of pain during 2006-2008 was undertaken. Findings including type and intensity of pain, initial evaluation, treatment initiated, and other associated symptoms were recorded at the initial visit and 1 week, 1 month, and 6 months thereafter. Pain with a burning, radiating, or shooting component was considered to be neuropathic.

RESULTS

The prevalence of neuropathic pain in cancer pain patients was found to be 11.8%. Oral morphine emerged as the commonest cancer pain management modality (95.8% of patients). However, 29.89% of our patients with neuropathic pain required interventional blocks for adequate pain relief.

CONCLUSION

The present study highlights the significance of neuropathic pain as an integral component of cancer pain and further provides insight into its management.

摘要

背景

癌症疼痛通常是难治性的,对生活质量有很大影响。伤害感受性疼痛很容易识别,并且可以使用常规镇痛药进行管理。神经病理性成分使癌症疼痛难以管理。癌症患者神经病理性疼痛的流行病学尚未得到很好的记录。

研究目的

本回顾性研究试图在印度一家三级癌症中心的疼痛和姑息治疗诊所,确定在 2 年内癌症患者神经病理性疼痛的患病率。该研究还旨在描述缓解神经病理性癌症疼痛的方法。

材料和方法

对 2006 年至 2008 年期间因疼痛就诊的 3238 例癌症患者进行了回顾性分析。在初次就诊时以及此后 1 周、1 个月和 6 个月记录了发现,包括疼痛类型和强度、初始评估、开始的治疗以及其他相关症状。有烧灼感、放射性或刺痛感的疼痛被认为是神经病理性疼痛。

结果

在癌症疼痛患者中,神经病理性疼痛的患病率为 11.8%。口服吗啡是最常见的癌症疼痛管理方式(95.8%的患者)。然而,我们有 29.89%的神经病理性疼痛患者需要进行介入性阻滞以获得充分的疼痛缓解。

结论

本研究强调了神经病理性疼痛作为癌症疼痛的一个组成部分的重要性,并进一步提供了对其管理的深入了解。

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