Jakob H, Dubois P, Eisen H, Jacob F
C R Acad Hebd Seances Acad Sci D. 1978 Jan;286(1):109-11.
HMBA induces differentiation in the whole population of some multipotential embryonic carcinoma cells. Morphological, biochemical and immunological changes can be observed even after short treatment. The cells lose the embryonal F9 antigen without acquiring H-2 antigens.
六亚甲基双乙酰胺可诱导部分多能胚胎癌细胞群体发生分化。即使经过短期处理,也能观察到形态、生化和免疫学变化。细胞失去胚胎F9抗原,且未获得H-2抗原。