Department of Pediatrics, University of Colorado Denver-School of Medicine, Denver Health and Hospitals, 501 28th St., Denver, CO 80205, USA.
J Immigr Minor Health. 2011 Jun;13(3):426-33. doi: 10.1007/s10903-010-9370-4.
(1) Describe gestational diabetes mellitus (GDM) prevalence time trends in USborn (USWH) and Mexico-born (MWH), white Hispanic Colorado women and (2) Determine effect of maternal birthplace on GDM prevalence. Retrospective population-based study of 1995-2004 Colorado birth certificate data for live, singleton births to white, Hispanic mothers estimated prevalence, trends, and association of GDM and maternal birthplace. Univariate, bivariate and logistic regression analyses were conducted. GDM prevalence in 154,957 births increased in both USWH (1.77-2.53%, P < 0.0001) and MWH (2.38-3.08%, P < 0.0001). Over study years, MWH had higher crude odds (OR = 1.30; 95% CI = 1.22-1.38) for developing GDM than USWH. Adjustment for maternal age and maternal education reduced GDM risk by birth country (OR = 1.05; 95% CI = 0.98-1.13, P = ns). GDM prevalence increased in both US-born and Mexico-born, white, Hispanic Colorado women. Mexico-born immigrant women may have increased risk for GDM compared with their USborn counterparts. Lower education attainment may be determinant of disease risk.
（1）描述美国出生（USWH）和墨西哥出生（MWH）、白西班牙裔科罗拉多州妇女中妊娠糖尿病（GDM）的流行时间趋势，并（2）确定产妇出生地对 GDM 流行率的影响。这是一项回顾性基于人群的研究，分析了 1995-2004 年科罗拉多州出生证明数据中活产、单胎、白西班牙裔母亲的 GDM 患病率、趋势以及与产妇出生地的关系。进行了单变量、双变量和逻辑回归分析。在美国出生的白人西班牙裔妇女（1.77-2.53%，P < 0.0001）和在墨西哥出生的白人西班牙裔妇女（2.38-3.08%，P < 0.0001）中，GDM 的患病率均有所增加。在研究期间，与美国出生的妇女相比，墨西哥出生的妇女发生 GDM 的粗比值比（OR）更高（OR=1.30；95%可信区间（CI）为 1.22-1.38）。调整产妇年龄和受教育程度后，出生国降低了 GDM 风险（OR=1.05；95%CI=0.98-1.13，P=ns）。在美国出生和在墨西哥出生的白人西班牙裔科罗拉多州妇女中，GDM 的患病率均有所增加。与美国出生的妇女相比，墨西哥出生的移民妇女可能具有更高的 GDM 发病风险。受教育程度较低可能是疾病风险的决定因素。
