Wang Fuhua, Hu Xiao, Chen Hailin, Ma Jianping, Wang Jianxin, Hou Aijun
School of Pharmacy, Fudan University, Shanghai 201203, China.
Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(16):2057-9.
To investigate the alkaloids in the roots of Dactylicapnos scanden (D. Don) Hutch.
The compounds were isolated by various column chromatographic methods. The structures were elucidated by spectroscopic analysis.
Eight compounds were isolated and identified as d-isocorydine (1), protopine (2), d-magnoflorine (3), d-isocorydine-beta-N-oxide (4), d-corydine-alpha-N-oxide (5), d-corydine-beta-N-oxide (6), 6S, 6aS-N-methyllaurotetanine-alpha-N-oxide (7), and 6R, 6aS-N-methyllaurotetanine-beta-N-oxide (8).
Compounds 4-8 were isolated from this species and the genus Dactylicapnos for the first time.
研究紫金龙（Dactylicapnos scanden (D. Don) Hutch.）根中的生物碱。
采用多种柱色谱法分离化合物。通过光谱分析确定结构。
分离得到8个化合物，分别鉴定为d-异紫堇定（1）、原阿片碱（2）、d-木兰碱（3）、d-异紫堇定-β-N-氧化物（4）、d-紫堇定-α-N-氧化物（5）、d-紫堇定-β-N-氧化物（6）、6S, 6aS-N-甲基劳丹碱-α-N-氧化物（7）和6R, 6aS-N-甲基劳丹碱-β-N-氧化物（8）。
化合物4 - 8首次从该物种及紫金龙属中分离得到。
