Fox G E, Van Wesep R, Resau J H, Sun C C
Department of Pathology, University of Maryland School of Medicine, Baltimore.
Arch Pathol Lab Med. 1991 Jul;115(7):726-8.
The prevalence of the human immunodeficiency and hepatitis viruses has led to considerable concern by health care workers about safer means of examining surgical pathological specimens. The human placenta needs to be examined when there are complications during pregnancy, labor, and delivery; when the fetus is born with apparent problems; and when the delivered placenta is abnormal. Placentas are routinely immersion fixed with neutral buffered 3.7% to 4.0% formaldehyde solution before examination and without obtaining a fresh weight. This study was undertaken to determine if there was a significant change in weight between a fresh and fixed placenta. The results show a 7.67% increase in placental weight after formaldehyde fixation for 24 hours. Thus, the practice of formaldehyde fixation prior to weighing and examination can be continued and still allow for accurate estimation of fresh placental weight.
人类免疫缺陷病毒和肝炎病毒的流行，引发了医护人员对更安全的手术病理标本检查方法的高度关注。在孕期、分娩期出现并发症时，胎儿出生时有明显问题时，以及娩出的胎盘异常时，都需要对人胎盘进行检查。胎盘在检查前通常用3.7%至4.0%的中性缓冲甲醛溶液浸泡固定，且不称取新鲜重量。本研究旨在确定新鲜胎盘与固定胎盘之间的重量是否存在显著变化。结果显示，甲醛固定24小时后胎盘重量增加了7.67%。因此，在称重和检查前进行甲醛固定的做法可以继续，并且仍能准确估算新鲜胎盘的重量。
