Department of Forensic Medicine and Pathology, District General Hospital, Vavuniya, Sri Lanka.
Department of Forensic Medicine and Pathology, Teaching Hospital, Jaffna, Sri Lanka.
J Int Med Res. 2023 May;51(5):3000605231172895. doi: 10.1177/03000605231172895.
Placental pathology is a well-known cause of perinatal and neonatal mortality and morbidity, and may correlate with placental growth, which can be assessed indirectly by anthropometric placental measurements. The aim of this cross-sectional study was to investigate mean placental weight and its relationship with birthweight and maternal body mass index (BMI).
Fresh (not formalin fixed) consecutively delivered placentae of term newborns (37-42 weeks), collected between February 2022 and August 2022, and the mothers and newborns, were included. Mean placental weight, birthweight and maternal BMI were calculated. Pearson's correlation coefficient, linear regression, and one-way analysis of variance were used to analyse continuous and categorical data.
Out of 390 samples, 211 placentae (with 211 newborns and mothers) were included in this study after exclusion criteria were applied. Mean placental weight was 494.45 ± 110.39 g, and mean term birth weight/placental weight ratio was 6.21 ± 1.21 (range, 3.35-11.62 g). Placental weight was positively correlated with birthweight and maternal BMI, but not with newborn sex. Linear regression effect estimation of placental weight on birthweight revealed a medium correlation ( = 0.212; formula, 1.4553 × X + 2246.7, where X is placental weight [g]).
Placental weight was revealed to positively correlate with birthweight and maternal BMI.
胎盘病理是围产儿和新生儿死亡率和发病率的已知原因，并且可能与胎盘生长相关，胎盘生长可以通过人体测量胎盘测量间接评估。本横断面研究的目的是调查平均胎盘重量及其与出生体重和产妇体重指数（BMI）的关系。
纳入 2022 年 2 月至 2022 年 8 月连续采集的足月（37-42 周）新生儿的新鲜（非福尔马林固定）胎盘，以及母亲和新生儿。计算平均胎盘重量、出生体重和产妇 BMI。使用 Pearson 相关系数、线性回归和单因素方差分析分析连续和分类数据。
在 390 个样本中，应用排除标准后，本研究纳入了 211 个胎盘（211 名新生儿和母亲）。平均胎盘重量为 494.45±110.39g，平均足月出生体重/胎盘重量比为 6.21±1.21（范围为 3.35-11.62g）。胎盘重量与出生体重和产妇 BMI 呈正相关，但与新生儿性别无关。胎盘重量对出生体重的线性回归效应估计显示出中等相关性（ = 0.212；公式为 1.4553×X+2246.7，其中 X 为胎盘重量[g]）。
胎盘重量与出生体重和产妇 BMI 呈正相关。
