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马缨丹、藿香和飞机草精油的化学成分和抗菌活性。

Chemical composition and antibacterial activity of essential oils of Lantana camara, Ageratum houstonianum and Eupatorium adenophorum.

机构信息

Indian Veterinary Research Institute, Regional Station, Palampur, Himachal Pradesh, India.

出版信息

Pharm Biol. 2010 May;48(5):539-44. doi: 10.3109/13880200903193336.

DOI:10.3109/13880200903193336
PMID:20645797
Abstract

Essential oils have applications in folk medicine, food preservation, and as feed additives. The essential oils of Lantana camara Linn. (Verbenaceae), Ageratum houstonianum Mill. (Asteraceae) and Eupatorium adenophorum Spreng. (Asteraceae) were analyzed by Gas chromatography-mass spectrometry (GCMS). In L. camara oil, of the total identified (83.91%) volatile constituents, five constituents [3,7,11-trimethyl-1,6,10-dodecatriene (28.86%), beta-caryophyllene (12.28%), zingiberene (7.63%), gamma-curcumene (7.50%) and alpha-humulene (3.99%)] represented the major ones. In A. houstonianum oil, among the total identified volatile constituents (94.51%), three [precocene-II (52.64%), precocene-I (22.45%) and beta-caryophyllene (9.66%)] represented the major ones. In E. adenophorum oil, of the total identified volatile constituents (84.95%), six [1-napthalenol (17.50%), alpha-bisabolol (9.53%), bornyl acetate (8.98%), beta-bisabolene (6.16%), germacrene-D (5.74%) and alpha- phellandrene (3.85%)] represented the major ones. The antibacterial activity expressed as Minimum Bactericidal Concentration (MBC) (microg/mL) was determined by the broth dilution method. The essential oil of E. adenophorum had antibacterial activity against Arthrobacter protophormiae, Escherichia coli, Micrococcus luteus, Rhodococcus rhodochrous, and Staphylococcus aureus with MBC values of 200, 100, 100, 12.5, and 200, respectively. The essential oil of A. houstonianum showed antibacterial activity against M. luteus and R. rhodochrous with MBC of 100 and 12.5, but not against A. protophormiae, E. coli, and S. aureus. The essential oil of L. camara showed antibacterial activity against A. protophormiae, M. luteus, R. rhodochrous and S. aureus with MBC of 50, 25, 12.5, and 200, respectively, but not against E. coli. MBC was lowest for R. rhodochrous for all the three essential oils.

摘要

香精油在民间医学、食品保存和饲料添加剂中有应用。通过气相色谱-质谱联用(GCMS)分析了马缨丹(马鞭草科)、藿香(菊科)和紫茎泽兰(菊科)的精油。在马缨丹油中,总鉴定的(83.91%)挥发性成分中,有五个成分[3,7,11-三甲基-1,6,10-十二碳三烯(28.86%),β-石竹烯(12.28%),姜烯(7.63%),γ-姜黄烯(7.50%)和α-葎草烯(3.99%)]代表主要成分。在藿香油中,总鉴定的挥发性成分(94.51%)中,有三个成分[precocene-II(52.64%),precocene-I(22.45%)和β-石竹烯(9.66%)]代表主要成分。在紫茎泽兰油中,总鉴定的挥发性成分(84.95%)中,有六个成分[1-萘酚(17.50%),α-大根香叶醇(9.53%),乙酸龙脑酯(8.98%),β-大根香叶烯(6.16%),大根香叶二烯(5.74%)和α-水芹烯(3.85%)]代表主要成分。最小杀菌浓度(MBC)(微克/毫升)的肉汤稀释法确定了抗菌活性。紫茎泽兰精油对节杆菌、大肠杆菌、藤黄微球菌、红球菌和金黄色葡萄球菌具有抗菌活性,MBC 值分别为 200、100、100、12.5 和 200。藿香精油对藤黄微球菌和红球菌具有抗菌活性,MBC 值分别为 100 和 12.5,但对节杆菌、大肠杆菌和金黄色葡萄球菌没有抗菌活性。马缨丹精油对节杆菌、藤黄微球菌、红球菌和金黄色葡萄球菌具有抗菌活性,MBC 值分别为 50、25、12.5 和 200,但对大肠杆菌没有抗菌活性。对于三种精油,MBC 对红球菌最低。

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