Department of Building and Civil Engineering, Faculty for the Built Environment, University of Malta, Malta, Italy.
Int Endod J. 2011 Jan;44(1):9-20. doi: 10.1111/j.1365-2591.2010.01774.x.
To evaluate (i) the sealing ability of two sealers, mineral trioxide aggregate sealer (MTAS) and Pulp Canal Sealer (PCS), used with gutta-percha utilizing the fluid filtration method, (ii) leaching and surface characteristics in Hank's balanced salt solution (HBSS) over a period of time.
Surface characteristics in HBSS were evaluated under the scanning electron microscope after 1 and 28 days, and the leaching of both sealers were assessed by inductively coupled plasma atomic absorption spectrometry (ICP-AAS). In addition, 24 single rooted extracted teeth were root filled using warm vertical compaction with either MTAS or PCS used as sealers with gutta-percha. Four teeth were used as positive and negative controls. Sealing ability was evaluated after 1 or 28 days using the fluid filtration method.
Mineral trioxide aggregate sealer exhibited crystalline deposits rich in calcium and phosphorus on its surface when in contact with a physiological solution. These crystalline deposits were absent in PCS and on MTAS stored at 100% humidity. The sealing ability of MTAS was similar to that of PCS.
The novel sealer based on mineral trioxide aggregate had comparable sealing ability to a proprietary brand sealer cement. In contact with a simulated body fluid, the MTA sealer released calcium ions in solution that encouraged the deposition of calcium phosphate crystals.
（i）评估两种密封剂——矿化三氧化物聚合体（MTAS）和牙髓腔封闭剂（PCS）——在使用牙胶时的密封能力，采用液体过滤法；（ii）在一段时间内 HBSS 中浸出和表面特性。
在 1 天和 28 天后，使用扫描电子显微镜评估 HBSS 中的表面特性，通过电感耦合等离子体原子吸收光谱法（ICP-AAS）评估两种密封剂的浸出情况。此外，使用热垂直加压法，将 24 颗单根拔出的牙齿用 MTAS 或 PCS 作为密封剂进行根管填充，其中 4 颗作为阳性和阴性对照。在 1 天或 28 天后，使用液体过滤法评估密封能力。
当与生理溶液接触时，矿化三氧化物聚合体表面显示出富含钙和磷的结晶沉积物。在 PCS 中以及在 100%湿度下储存的 MTAS 中没有这些结晶沉积物。MTAS 的密封能力与 PCS 相似。
基于矿化三氧化物聚合体的新型密封剂与专有品牌的密封剂水泥具有相似的密封能力。与模拟体液接触时，MTA 密封剂会将钙离子释放到溶液中，从而促进磷酸钙晶体的沉积。
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