神经性贪食症、胃食管反流病、口腔黏膜病患者与健康人群口腔黏膜 pH 值的比较。
Comparison of oral mucosal pH values in bulimia nervosa, GERD, BMS patients and healthy population.
机构信息
Department of Oral Medicine, Salivary Gland Clinic and Saliva Diagnostics Laboratory, Hebrew University-Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
出版信息
Oral Dis. 2010 Nov;16(8):807-11. doi: 10.1111/j.1601-0825.2010.01692.x.
OBJECTIVES
The aim of this study was to compare the oral mucosal pH in healthy individuals to patients with gastroesophageal reflux disease (GERD), Bulimia nervosa (BN) and burning mouth syndrome (BMS).
SUBJECTS AND METHODS
Using a flat pH meter sensor, pH levels were established in eight mucosal sites in 26 healthy individuals, 26 GERD patients, 22 BN patients and 29 BMS patients.
RESULTS
A significantly lower pH was found in the BN and GERD groups (6.38 ± 00.45, 6.51 ± 0.32 respectively, P < 0.05) and a higher, but non-significant, pH level in the BMS group (7.01 ± 0.34, P > 0.05) compared with the control (C) group (6.82 ± 0.33).
CONCLUSIONS
BMS patients showed no pH differences from C group. The mucosa of BN and GERD patients was significantly acidic relative with controls; thus this simple technique may serve as a diagnostic tool for identifying gastro-esophageal conditions.
目的
本研究旨在比较健康个体、胃食管反流病（GERD）患者、神经性贪食症（BN）患者和灼口综合征（BMS）患者的口腔黏膜 pH 值。
受试者和方法
使用平面 pH 计传感器，在 26 名健康个体、26 名 GERD 患者、22 名 BN 患者和 29 名 BMS 患者的 8 个黏膜部位确定 pH 值。
结果
BN 组和 GERD 组的 pH 值明显较低（分别为 6.38 ± 00.45、6.51 ± 0.32，P < 0.05），BMS 组的 pH 值较高，但无统计学意义（7.01 ± 0.34，P > 0.05），与对照组（C）组（6.82 ± 0.33）相比。
结论
BMS 患者的黏膜 pH 值与 C 组无差异。BN 和 GERD 患者的黏膜明显呈酸性，相对对照组；因此，这种简单的技术可以作为识别胃食管疾病的诊断工具。
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