胃食管反流病中的口腔pH值
Oral pH in gastroesophageal reflux disease.
作者信息
Sujatha S, Jalihal Umesh, Devi Yashoda, Rakesh N, Chauhan Pallavi, Sharma Shivani
机构信息
Department of Oral Medicine and Radiology, M S Ramaiah Dental College and Hospital, MSRIT Post, M S R Nagar, Bengaluru, 560 054, India.
Department of Gastroenterology, M S Ramaiah Dental College and Hospital, MSRIT Post, M S R Nagar, Bengaluru, 560 054, India.
出版信息
Indian J Gastroenterol. 2016 May;35(3):186-9. doi: 10.1007/s12664-016-0659-7. Epub 2016 May 23.
AIMS AND OBJECTIVES
The aim of this study is to compare surface pH in various parts of the oral cavity between patients with gastroesophageal reflux disease (GERD) and healthy controls.
METHODS
Using a flat pH meter sensor, fixed electrode pen type digital pH meter, oral pH levels were assessed at different mucosal sites among 34 GERD patients and 32 healthy controls. Salivary flow rates and buffering capacity were also assessed in them. A thorough oral examination was performed to screen for any oral and dental changes.
RESULT
A significantly lower pH of 6.65 ± 0.13 (mean ± SD) was found in the GERD group compared to control group 7.23 ± 0.12 (p < 0.05). Least pH was found in the floor of the mouth 6.594 ± 0.17 and highest in the lower labial mucosa among the GERD patients. Salivary flow rate and buffering capacity were low in these patients. Significant changes were noticed in the hard and soft tissues of the oral cavity among the GERD group.
CONCLUSION
Oral mucosal pH is altered in GERD patients and may contribute to effects on the oral cavity.
目的
本研究旨在比较胃食管反流病（GERD）患者与健康对照者口腔各部位的表面pH值。
方法
使用平面pH计传感器、固定电极笔式数字pH计，对34例GERD患者和32例健康对照者的不同黏膜部位的口腔pH值进行评估。同时评估他们的唾液流速和缓冲能力。进行全面的口腔检查以筛查任何口腔和牙齿变化。
结果
GERD组的pH值显著低于对照组，分别为6.65±0.13（平均值±标准差）和7.23±0.12（p<0.05）。GERD患者中，口腔底部的pH值最低，为6.594±0.17，下唇黏膜的pH值最高。这些患者的唾液流速和缓冲能力较低。GERD组患者口腔的硬组织和软组织出现了明显变化。
结论
GERD患者的口腔黏膜pH值发生改变，可能对口腔产生影响。
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