Allergy Department, Cambridge University NHS Foundation Trust, Cambridge, UK.
Clin Exp Allergy. 2010 Aug;40(8):1116-29. doi: 10.1111/j.1365-2222.2010.03557.x.
This guideline advises on the management of patients with egg allergy. Most commonly, egg allergy presents in infancy, with a prevalence of approximately 2% in children and 0.1% in adults. A clear clinical history and the detection of egg white-specific IgE (by skin prick test or serum assay) will confirm the diagnosis in most cases. Egg avoidance advice is the cornerstone of management. Egg allergy often resolves and re-introduction can be achieved at home if reactions have been mild and there is no asthma. Patients with a history of severe reactions or asthma should have reintroduction guided by a specialist. All children with egg allergy should receive measles, mumps and rubella (MMR) vaccination. Influenza and yellow fever vaccines should only be considered in egg-allergic patients under the guidance of an allergy specialist. This guideline was prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI) and is intended for allergists and others with a special interest in allergy. The recommendations are evidence-based but where evidence was lacking consensus was reached by the panel of specialists on the committee. The document encompasses epidemiology, risk factors, diagnosis, treatment, prognosis and co-morbid associations.
本指南针对鸡蛋过敏患者的管理提供建议。鸡蛋过敏最常发生于婴儿期，儿童中的发病率约为 2%，成人中的发病率约为 0.1%。大多数情况下，明确的临床病史和蛋清特异性 IgE 的检测（通过皮肤点刺试验或血清检测）可确认诊断。避免食用鸡蛋是管理的基石。如果过敏反应较轻且无哮喘，那么过敏通常会得到缓解，并且可以在家中重新引入鸡蛋。有严重过敏反应或哮喘病史的患者应在过敏专家的指导下进行重新引入。所有鸡蛋过敏的儿童均应接种麻疹、腮腺炎和风疹（MMR）疫苗。流感和黄热病疫苗应仅在过敏专家的指导下，考虑用于鸡蛋过敏患者。本指南由英国过敏与临床免疫学学会（BSACI）标准护理委员会（SOCC）制定，供过敏专家和其他对过敏有特殊兴趣的人员使用。这些建议基于证据，但在证据不足的情况下，委员会专家组达成了共识。本文件涵盖了流行病学、危险因素、诊断、治疗、预后和合并症关联。
