Jeon You Hoon
Department of Pediatrics, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.
Clin Exp Pediatr. 2020 Dec;63(12):463-468. doi: 10.3345/cep.2019.00780. Epub 2020 May 14.
Pollen-food allergy syndrome (PFAS) is an immunoglobulin E-mediated immediate allergic reaction caused by cross-reactivity between pollen and the antigens of foods-such as fruits, vegetables, or nuts-in patients with pollen allergy. A 42.7% prevalence of PFAS in Korean pediatric patients with pollinosis was recently reported. PFAS is often called oral allergy syndrome because of mild symptoms such as itching, urticaria, and edema mainly in the lips, mouth, and pharynx that appear after food ingestion. However, reports of systemic reactions such as anaphylaxis have been increasing recently. This diversity in the degree of symptoms is related to the types of trigger foods and the characteristics of allergens, such as heat stability. When pediatric patients with pollen allergy are treated, attention should be paid to PFAS and an active effort should be made to diagnose it.
花粉 - 食物过敏综合征（PFAS）是一种由花粉与食物（如水果、蔬菜或坚果）抗原之间的交叉反应引起的免疫球蛋白E介导的速发型过敏反应，发生于花粉过敏患者。最近有报道称，韩国花粉症儿科患者中PFAS的患病率为42.7%。由于摄入食物后主要在嘴唇、口腔和咽部出现瘙痒、荨麻疹和水肿等轻微症状，PFAS常被称为口腔过敏综合征。然而，最近关于过敏反应等全身反应的报道一直在增加。症状程度的这种多样性与引发过敏的食物类型以及过敏原的特性（如热稳定性）有关。在治疗花粉过敏的儿科患者时，应关注PFAS并积极努力进行诊断。
