对乙酰氨基酚引起的大疱性固定性药疹：1例儿科病例报告。

Bullous Fixed Drug Eruption Induced by Paracetamol: Report of a Pediatric Case.

作者信息

Nino Massimiliano, Francia Maria Grazia, Costa Claudia, Scalvenzi Massimiliano

机构信息

Department of Dermatology, University Federico II of Naples, Naples, Italy.

出版信息

Case Rep Dermatol. 2009 Oct 16;1(1):56-59. doi: 10.1159/000243728.

DOI:10.1159/000243728

PMID:20652116

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2895212/

Abstract

Drug eruptions are among the most common adverse drug reactions, affecting approximately 3% of hospitalized patients. A fixed drug eruption (FDE) is a distinct drug-induced reaction pattern that characteristically recurs at the same skin or mucosal site. We report a case of a 2-year-old girl with bullous FDE due to Tachipirina syrup, a preparation containing paracetamol, a commonly used nonsteroidal anti-inflammatory drug in Italy.

摘要

药物疹是最常见的药物不良反应之一，约3%的住院患者会受到影响。固定性药疹（FDE）是一种独特的药物诱发反应模式，其特征是在相同的皮肤或黏膜部位反复出现。我们报告一例2岁女童因服用塔奇皮里纳糖浆引发大疱性固定性药疹的病例，该糖浆制剂含有对乙酰氨基酚，这是意大利一种常用的非甾体抗炎药。