General Intensive Care Unit, Raymond Poincaré Hospital (AP-HP), University of Versailles Saint Quentin en Yvelines, 104 Boulevard Raymond Poincaré, 92380, Garches, France.
J Clin Monit Comput. 2010 Aug;24(4):289-93. doi: 10.1007/s10877-010-9247-z. Epub 2010 Jul 23.
This monocentric prospective study was conducted to determine if tissue oxygen saturation measured non invasively over masseter muscle site (Masseter-StO2) can predict the central venous oxygen saturation (ScvO2) level in severe sepsis and septic shock.
Sixteen consecutive patients with severe sepsis (n = 10) or septic shock (n = 6) were included in this study. ScvO2 was measured on blood samples taken from the superior vena cava via the distal line of a central venous catheter. Masseter-StO2 was measured with a 25 mm depth infrared probe, applied and attached to the skin using transparent adhesive shields. Fifty-seven pairs of measures were obtained.
Mean ScvO2 was 76.5% (median 81, standard deviation 15, range [14-94]). Twenty percent of the ScvO2 measures were lower than 70%. Seven out of 16 patients had at least one measure of 70% or less. Mean Masseter-StO2 was 81% (median 91, standard deviation 18, range [29-98]). We found a significant association between ScvO2 and Masseter-StO2 (correlation coefficient 0.65, P < 0.01), however agreement was moderate.
In patients with severe sepsis or septic shock, non invasive recording of Masseter-StO2 was significantly associated with ScvO2 Further studies are required to determine the usefulness of Masseter-StO2 guided management of severe sepsis or septic shock.
本单中心前瞻性研究旨在确定经颧骨肌部位（Masseter-StO2）无创测量的组织氧饱和度是否可预测严重脓毒症和感染性休克患者的中心静脉血氧饱和度（ScvO2）水平。
本研究纳入了 16 例连续的严重脓毒症（n=10）或感染性休克（n=6）患者。通过中心静脉导管的远端线从上腔静脉采集血样测量 ScvO2。使用深度为 25mm 的红外探头测量 Masseter-StO2，将探头放置在颧骨肌上，并用透明的粘性护罩固定。共获得了 57 对测量值。
平均 ScvO2 为 76.5%（中位数 81，标准差 15，范围 [14-94]）。20%的 ScvO2 测量值低于 70%。16 例患者中有 7 例至少有一次测量值低于 70%。平均 Masseter-StO2 为 81%（中位数 91，标准差 18，范围 [29-98]）。我们发现 ScvO2 与 Masseter-StO2 之间存在显著相关性（相关系数 0.65，P<0.01），但一致性为中等。
在严重脓毒症或感染性休克患者中，无创记录的 Masseter-StO2 与 ScvO2 显著相关。需要进一步研究以确定 Masseter-StO2 指导严重脓毒症或感染性休克管理的实用性。
