Simmer K, Lort-Phillips L, James C, Thompson R P
Gastrointestinal Laboratory, Rayne Institute, St Thomas' Hospital, London, UK.
Eur J Clin Nutr. 1991 Mar;45(3):139-44.
A double-blind randomised trial of oral zinc supplementation was carried out during the last two trimesters of pregnancy. Fifty-six women at risk of delivering a small-for-gestational-age baby received either zinc supplement (22.5 mg daily) or placebo. Twenty-nine of the women were compliant. Zinc significantly reduced the incidence of intrauterine growth retardation, and most measured indices of labour and fetal health were better in the supplemented group. Larger studies are now needed to confirm a role for selective zinc supplementation in at-risk pregnancies.
在妊娠最后两个阶段进行了一项口服锌补充剂的双盲随机试验。56名有分娩小于胎龄儿风险的女性接受了锌补充剂（每日22.5毫克）或安慰剂。其中29名女性依从性良好。锌显著降低了宫内生长受限的发生率，补充锌的组中大多数测量的分娩和胎儿健康指标都更好。现在需要更大规模的研究来证实选择性锌补充剂在高危妊娠中的作用。
