Hong Z Y, Zhang Y W, Xu J D, Zhou J D, Gao X L, Liu X G, Shi Y Y
Child Health Department, Xinhua Hospital, Shanghai Second Medical University.
Chin Med J (Engl). 1992 Oct;105(10):844-8.
This study was made to determine whether zinc deficiency is one of the factors involved in growth retardation of infants of high-risk pregnancies. The high risk factors were hypertension of pregnancy, diabetes mellitus, congenital heart disease, chronic nephritis, rheumatic heart disease and hyperthyroidism. 102 neonatal infants were divided into 3 groups: breast fed group, 37 cases; test group, 32 cases formula-fed with supplementary zinc 1.14-2.28 mg/kg/d; and control group, 33 cases formula-fed and supplemented with Vitamin B complex as placebo. The groups were divided by double-blind and randomized method. There were no differences in the 3 groups in sex ratio, growth status and serum zinc concentration at the beginning of the study. Anthropometric data were obtained at 0, 3 and 6 months.
本研究旨在确定锌缺乏是否为高危妊娠婴儿生长发育迟缓的相关因素之一。高危因素包括妊娠高血压、糖尿病、先天性心脏病、慢性肾炎、风湿性心脏病和甲状腺功能亢进。102例新生儿分为3组：母乳喂养组，37例；试验组，32例，采用配方奶喂养并补充锌1.14 - 2.28毫克/千克/天；对照组，33例，采用配方奶喂养并补充复合维生素B作为安慰剂。分组采用双盲随机法。研究开始时，3组在性别比例、生长状况和血清锌浓度方面无差异。在0、3和6个月时获取人体测量数据。
