Elsayes Khaled M, Menias Christine O, Siegel Cary L, Narra Vamsidhar R, Kanaan Yassine, Hussain Hero K
Department of Radiology, University of Michigan Health System, Ann Arbor, MI 48109-0030, USA.
J Comput Assist Tomogr. 2010 Jul;34(4):548-53. doi: 10.1097/RCT.0b013e3181d529f2.
To study the magnetic resonance imaging characteristics of adrenal and extra-adrenal pheochromocytomas in the abdomen and pelvis.
We retrospectively reviewed 18 cases of pathologically proven cases of pheochromocytomas in the abdomen and pelvis. These patients have undergone magnetic resonance imaging evaluation before surgery. The study population included 10 men and 7 women (age range, 19-68 years; mean, 38 years). A consensus review of the magnetic resonance images was performed by 2 blinded expert observers. A qualitative evaluation was completed, and the tumors were classified by anatomical location, shape, T2 signal, contrast enhancement, and signal dropout on chemical shift pulse sequences.
On T2-weighted images, most lesions demonstrated mild to moderate increased signal intensity (SI) (n = 12), 5 lesions demonstrated a markedly increased SI, and only 1 lesion demonstrated an isointense SI on T2-weighted images.Five lesions demonstrated marked postcontrast enhancement. Three lesions demonstrated moderate enhancement, and 5 lesions demonstrated mild postcontrast enhancement.The pattern of enhancement was variable: 4 salt and pepper, 4 homogeneous, 3 heterogeneous, and 2 target with central necrosis and hemorrhage. None of the lesions contained significant amount of intracellular lipid, as no lesions demonstrated greater than 16.5% signal dropout on out-of-phase compared with in-phase pulse sequences.
研究腹部和盆腔肾上腺及肾上腺外嗜铬细胞瘤的磁共振成像特征。
我们回顾性分析了18例经病理证实的腹部和盆腔嗜铬细胞瘤病例。这些患者在手术前均接受了磁共振成像评估。研究对象包括10名男性和7名女性（年龄范围19 - 68岁；平均38岁）。由2名不知情的专家观察者对磁共振图像进行一致性评估。完成定性评估，并根据解剖位置、形态、T2信号、对比增强以及化学位移脉冲序列上的信号丢失情况对肿瘤进行分类。
在T2加权图像上，大多数病变表现为轻度至中度信号强度（SI）增加（n = 12），5个病变表现为明显信号强度增加，只有1个病变在T2加权图像上表现为等信号强度。5个病变表现为明显的对比增强后强化。3个病变表现为中度强化，5个病变表现为轻度对比增强后强化。强化模式各异：4个呈“椒盐”样，4个均匀强化，3个不均匀强化，2个呈中央坏死和出血的靶样强化。所有病变均未含有大量细胞内脂质，因为与同相位脉冲序列相比，没有病变在反相位上表现出大于16.5%的信号丢失。
