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苯二氮䓬类药物的使用与社区老年人的睡眠质量。

Benzodiazepine use and quality of sleep in the community-dwelling elderly population.

机构信息

Faculte de Pharmacie, Universite de Montreal, Montreal, Quebec, G8B 1S5 Canada.

出版信息

Aging Ment Health. 2010 Sep;14(7):843-50. doi: 10.1080/13607861003781833.

Abstract

BACKGROUND

About 50% of the elderly population report being dissatisfied with their sleep. Although benzodiazepines are the most prescribed drugs to treat sleep complaints, the effectiveness of their use on the quality of sleep is not well documented.

OBJECTIVES

This study aimed to assess the association between benzodiazepine use and global sleep quality, as well as six components of sleep quality.

METHODS

Data from the cross-sectional Quebec Survey on Seniors' Health (n = 2798) conducted in 2005-2006 were used. Quality of sleep was self-reported and use of benzodiazepines was assessed during the previous year.

RESULTS

Benzodiazepine users reported poorer quality of sleep than non-users. The association between benzodiazepine use and each of the six quality of sleep components studied were similar except for the daytime dysfunction component.

CONCLUSION

The results suggest that there is no evidence that using benzodiazepines is associated with better quality of sleep than non-users in the elderly population. Future longitudinal population-based studies are needed to assess improvements in quality of sleep in the elderly associated with the use of benzodiazepines.

摘要

背景

约有 50%的老年人对自己的睡眠不满意。尽管苯二氮䓬类药物是治疗睡眠问题最常开的药物,但它们对睡眠质量的有效性并没有得到很好的记录。

目的

本研究旨在评估苯二氮䓬类药物的使用与总体睡眠质量以及睡眠质量的六个组成部分之间的关系。

方法

使用了 2005-2006 年进行的横断面魁北克老年人健康调查(n=2798)的数据。睡眠质量是自我报告的,并且在过去一年中评估了苯二氮䓬类药物的使用情况。

结果

苯二氮䓬类药物使用者报告的睡眠质量比非使用者差。苯二氮䓬类药物的使用与所研究的六个睡眠质量组成部分中的每一个都存在关联,但日间功能障碍组成部分除外。

结论

结果表明,没有证据表明在老年人中,使用苯二氮䓬类药物与非使用者相比,睡眠质量更好。未来需要进行基于人群的纵向研究,以评估与苯二氮䓬类药物使用相关的老年人睡眠质量的改善情况。

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