Centre forAddiction and Mental Health (CAMH), Public Health and Regulatory Policy, 33 Russell Street, Room 2035, Toronto, ON M5S2S1, Canada.
Alcohol Clin Exp Res. 2010 Nov;34(11):1871-8. doi: 10.1111/j.1530-0277.2010.01275.x.
Alcohol use disorders (AUD), i.e., alcohol dependence and abuse, are major contributors to burden of disease. A large part of this burden is because of disability. However, there is still controversy about the best disability weighting for AUD. The objective of this study was to provide an overview of alcohol-related disabilities.
Systematic literature review and expert interviews.
There is heterogeneity in experts' descriptions of disabilities related to AUD. The major core attributes of disability related to AUD are changes of emotional state, social relationships, memory and thinking. The most important supplementary attributes are anxiety, impairments of speech and hearing.
This review identified the main patterns of disability associated with AUD. However, there was considerable variability, and data on less prominent patterns were fragmented. Further and systematic research is required for increasing the knowledge on disability related to AUD and for application of interventions for reducing the associated burden.
酒精使用障碍（AUD），即酒精依赖和滥用，是疾病负担的主要原因之一。这部分负担很大程度上是因为残疾。然而，对于 AUD 的最佳残疾权重仍存在争议。本研究的目的是概述与酒精相关的残疾。
系统文献回顾和专家访谈。
专家对 AUD 相关残疾的描述存在异质性。与 AUD 相关的残疾的主要核心属性是情绪状态、社会关系、记忆和思维的变化。最重要的补充属性是焦虑、言语和听力障碍。
本综述确定了与 AUD 相关的残疾的主要模式。然而，存在相当大的差异，关于不太突出模式的数据较为分散。需要进一步进行系统研究，以增加对 AUD 相关残疾的认识，并应用干预措施来减轻相关负担。
