Gallagher M, Kapp B S, Musty R E, Driscoll P A
Science. 1977 Oct 28;198(4315):423-5. doi: 10.1126/science.20664.
beta-Adrenergic antagonists injected into the amygdala complex of rats trained in a passive avoidance task produced time-dependent and dose-dependent decreases in retention of the task. In addition, the effects observed with beta-adrenergic antagonists were both stereospecific and reversed by norepinephrine. The results support a role for an amygdala beta-adrenergic system in memory processes.
将β-肾上腺素能拮抗剂注射到经被动回避任务训练的大鼠杏仁核复合体中，会使该任务的记忆保持出现时间和剂量依赖性下降。此外，β-肾上腺素能拮抗剂所观察到的效应具有立体特异性，且可被去甲肾上腺素逆转。这些结果支持杏仁核β-肾上腺素能系统在记忆过程中发挥作用。
