Cortini R, Wilkie N M
J Gen Virol. 1978 May;39(2):259-80. doi: 10.1099/0022-1317-39-2-259.
The ordering of restriction endonuclease fragments of HSV-2 DNA for physical maps has been studied using molecular hybridization techniques and the cleavage of isolated restriction endonuclease fragments with further restriction endonucleases. Physical maps for the fragments produced by EcoRI, Hind III, Bgl II, Xba and Hpa I have been constructed. The mol. wt. of the various regions which constitute HSV-2 genome are very similar to the corresponding mol. wt. in the HSV-1 genome.
已使用分子杂交技术以及用其他限制性内切酶切割分离出的限制性内切酶片段的方法，对单纯疱疹病毒2型（HSV - 2）DNA的限制性内切酶片段进行排序以构建物理图谱。已构建了由EcoRI、Hind III、Bgl II、Xba和Hpa I产生的片段的物理图谱。构成HSV - 2基因组的各个区域的分子量与HSV - 1基因组中相应的分子量非常相似。
