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重度癌痛患者口服吗啡的处方实践

Oral morphine prescribing practices in severe cancer pain.

作者信息

B Barathi

机构信息

Department of Pain and Palliative Care, St.John's Medical College Hospital, Bangalore, India.

出版信息

Indian J Palliat Care. 2009 Jul;15(2):127-31. doi: 10.4103/0973-1075.58458.

Abstract

BACKGROUND

Nearly one million cancer patients in India need oral morphine for pain relief. Despite doctors prescribing oral morphine in our center, many cancer patients with severe pain found to be not facilitated with adequate pain relief.

AIM

This audit was conducted to look at the "oral morphine prescribing practices for severe cancer pain" at a tertiary care hospital.

MATERIALS AND METHODS

Twenty case files of patients, who were admitted with severe cancer pain, and receiving oral morphine were analyzed in pre- and posteducational session. Local standards were set to assess the adequacy of pain relief. Deficiency in achieving analgesia was found in preinterventional audit. A clinical audit was conducted before and after the educational session on oral morphine prescribing. The education for doctors and nurses focused on starting patients on morphine, titration, and administering rescue dose. Then local guidelines on oral morphine prescribing were circulated. And analysis of following factors were done following pre- and posteducational session: Pain intensity at the beginning of treatment, starting dose of morphine, increments in morphine dose, number of rescue doses given, and fall in pain intensity at the end of 1 week. The outcomes were compared with the standards.

RESULTS

Preintervention audit showed that only 50% of patients achieved adequate pain relief. Rescue dose was administered in only 20% of patients. While reaudit following the educational session showed that 80% of patients achieved adequate pain relief and 100% received rescue doses.

CONCLUSION

Educational sessions have significant impact on improving oral morphine prescribing practice among doctors and nurses. It was found failing to administer regular as well as rescue doses resulted in inadequate pain relief in patients receiving oral morphine.

摘要

背景

印度近100万癌症患者需要口服吗啡来缓解疼痛。尽管在我们中心医生开具了口服吗啡的处方,但许多重度疼痛的癌症患者仍未得到充分的疼痛缓解。

目的

本次审核旨在调查一家三级护理医院“重度癌症疼痛的口服吗啡处方开具情况”。

材料与方法

对20例因重度癌症疼痛入院并接受口服吗啡治疗的患者病历在教育课程前后进行分析。设定了当地标准来评估疼痛缓解的充分性。在干预前审核中发现镇痛效果存在不足。在关于口服吗啡处方开具的教育课程前后进行了临床审核。对医生和护士的教育重点是让患者开始使用吗啡、滴定以及给予解救剂量。随后分发了关于口服吗啡处方开具的当地指南。并在教育课程前后对以下因素进行了分析:治疗开始时的疼痛强度、吗啡起始剂量、吗啡剂量增加量、给予的解救剂量数量以及1周结束时疼痛强度的下降情况。将结果与标准进行比较。

结果

干预前审核显示只有50%的患者实现了充分的疼痛缓解。只有20%的患者给予了解救剂量。而教育课程后的重新审核显示80%的患者实现了充分的疼痛缓解,100%的患者接受了解救剂量。

结论

教育课程对改善医生和护士的口服吗啡处方开具实践有显著影响。发现未能给予常规剂量和解救剂量导致接受口服吗啡的患者疼痛缓解不充分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93bc/2902113/70db818b9829/IJPC-15-127-g001.jpg

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