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吗啡及其他阿片类药物用于癌症疼痛治疗:欧洲姑息治疗学会(EAPC)的建议

Morphine and alternative opioids in cancer pain: the EAPC recommendations.

作者信息

Hanks G W, Conno F, Cherny N, Hanna M, Kalso E, McQuay H J, Mercadante S, Meynadier J, Poulain P, Ripamonti C, Radbruch L, Casas J R, Sawe J, Twycross R G, Ventafridda V

机构信息

Palliative Medicine, University of Bristol, Bristol Haematology and Oncology Centre, UK.

出版信息

Br J Cancer. 2001 Mar 2;84(5):587-93. doi: 10.1054/bjoc.2001.1680.

DOI:10.1054/bjoc.2001.1680
PMID:11237376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2363790/
Abstract

An expert working group of the European Association for Palliative Care has revised and updated its guidelines on the use of morphine in the management of cancer pain. The revised recommendations presented here give guidance on the use of morphine and the alternative strong opioid analgesics which have been introduced in many parts of the world in recent years. Practical strategies for dealing with difficult situations are described presenting a consensus view where supporting evidence is lacking. The strength of the evidence on which each recommendation is based is indicated.

摘要

欧洲姑息治疗协会的一个专家工作组修订并更新了其关于吗啡在癌症疼痛管理中应用的指南。此处呈现的修订建议为吗啡以及近年来在世界许多地区引入的其他强效阿片类镇痛药的使用提供了指导。文中描述了应对困难情况的实用策略,并在缺乏支持证据的情况下给出了共识性观点。同时指出了每项建议所依据证据的力度。

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本文引用的文献

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Lancet. 1999 Jun 26;353(9171):2229-32. doi: 10.1016/S0140-6736(99)03528-X.
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Pain treatment and outcomes for patients with advanced cancer who receive follow-up care at home.接受居家后续护理的晚期癌症患者的疼痛治疗及治疗效果。
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Switching from morphine to oral methadone in treating cancer pain: what is the equianalgesic dose ratio?在癌症疼痛治疗中从吗啡转换为口服美沙酮:等效镇痛剂量比是多少?
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Comparison of the analgesic and intestinal effects of fentanyl and morphine in rats.芬太尼与吗啡对大鼠镇痛及肠道作用的比较。
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