Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, UKOX1 3TA.
Org Biomol Chem. 2010 Oct 7;8(19):4232-5. doi: 10.1039/c0ob00226g. Epub 2010 Jul 22.
Monofunctionalization of trehalose, a widely-found symmetric plant disaccharide, was studied in a microreactor to give valuable kinetic insights that have allowed improvements in desymmetrization yields and the development of a reaction sequence for large scale monofunctionalizations that allow access to probes of trehalose's biological function.
在微反应器中研究了广泛存在的对称植物二糖海藻糖的单官能化,为非对称化产率的提高提供了有价值的动力学见解,并开发了一种用于大规模单官能化的反应序列,从而获得了研究海藻糖生物学功能的探针。