Département microbiologie-infectiologie et immunologie, Faculté de médecine, Université Laval, Montreal, Quebec, Canada.
Clin Microbiol Infect. 2010 Aug;16(8):1044-53. doi: 10.1111/j.1469-0691.2010.03282.x.
In recent years, we have witnessed many transitions in healthcare systems around the globe. For example, population expansion and ageing, and the human immunodeficiency virus (HIV)-AIDS epidemics, have exerted pressure to decentralize the practice of healthcare outside of traditional settings to bring care to those in need. Upstream of patient management, diagnosis is aimed at adequately orienting medical decisions, and considerable efforts have been made to make this process faster and more efficient. However, there are several diseases and medical conditions that may/will benefit from technologies and tests that can be performed closer to the patient, at the point of care or even in the home. In this review, and in light of the paradox that technology and assay developers and healthcare officials must take into consideration for advancing human health in developed and developing countries, we present an overview of rapid diagnosis of infectious diseases at the point of care and of technologies that may contribute to enhancement of the worldwide point-of-care testing market.
近年来，我们见证了全球医疗体系的许多转变。例如，人口扩张和老龄化以及人类免疫缺陷病毒（HIV）-艾滋病的流行，给医疗保健实践带来了压力，需要将其从传统环境中分散出去，以便为有需要的人提供护理。在患者管理的上游，诊断旨在为医疗决策提供充分的指导，并且已经做出了相当大的努力来使这一过程更快、更高效。然而，有几种疾病和医疗状况可能/将受益于能够更接近患者、在护理点甚至在家庭中进行的技术和检测。在这篇综述中，考虑到技术和检测试剂开发者以及医疗保健官员必须考虑的在发达国家和发展中国家推进人类健康的悖论，我们概述了在护理点进行传染病的快速诊断以及可能有助于增强全球护理点检测市场的技术。
