Department of Pathology, Antiviral Research Center, University of California, San Diego, CA, USA.
Bioinformatics. 2010 Oct 1;26(19):2455-7. doi: 10.1093/bioinformatics/btq429. Epub 2010 Jul 29.
Datamonkey is a popular web-based suite of phylogenetic analysis tools for use in evolutionary biology. Since the original release in 2005, we have expanded the analysis options to include recently developed algorithmic methods for recombination detection, evolutionary fingerprinting of genes, codon model selection, co-evolution between sites, identification of sites, which rapidly escape host-immune pressure and HIV-1 subtype assignment. The traditional selection tools have also been augmented to include recent developments in the field. Here, we summarize the analyses options currently available on Datamonkey, and provide guidelines for their use in evolutionary biology. Availability and documentation: http://www.datamonkey.org.
Datamonkey 是一款流行的基于网络的系统,用于进化生物学中的系统发育分析工具。自 2005 年首次发布以来,我们已经扩展了分析选项,包括最近开发的用于重组检测、基因进化指纹识别、密码子模型选择、位点协同进化、位点鉴定的算法方法,这些方法可以快速逃避宿主免疫压力和 HIV-1 亚型分配。传统的选择工具也得到了增强,包括该领域的最新发展。在这里,我们总结了 Datamonkey 目前提供的分析选项,并为它们在进化生物学中的应用提供了指导。可用性和文档:http://www.datamonkey.org。