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[食管癌切除术后肠道移植的功能研究]

[Functional study of intestinal transplants after esophagectomy].

作者信息

Del Poli M, Mioli P, Gasparri G, Casalegno P A, Camandona M, Bronda M, Albertino B, Cassolino P

机构信息

Istituto di Patologia Speciale Chirurgica, Università di Torino.

出版信息

Minerva Chir. 1991 Apr 15;46(7 Suppl):241-5.

PMID:2067688
Abstract

The Authors contribute their experience covering 228 cases of esophagoplasty after esophagectomy for cancer of the esophagus and of the esophagogastric junction, from 1980 to 1989. Thirty four of these patients (24 EGP, 8 EDP, 2 ECP) underwent accurate functional investigation by X-ray, manometry, pH-metry and scintigraphy. The investigation into esophagogastroplasty in particular revealed that the transposed organ is devoid of motor activity and that emptying is therefore achieved by gravity. It was also shown that the entity of the alkaline, acid and mixed-type reflux is linked to the site of the anastomosis: greater proximity of the anastomosis translates into lower involvement. An investigation into esophagojejunoplasty, instead, highlighted normal motor function: no cases presented reflux of the alkaline type. The two cases of colon plasty investigated presented efficient emptying even though manometry could not detect the presence of motor waves of the propulsive type. The authors conclude that, although the jejunum constitutes the best prosthetic element to transpose from the functional point of view, highly inconsistent and precarious vascularization limits the use of this organ to the higher anastomoses only. Therefore the Authors claim that the stomach, despite its tendency to behave as an inert tube, is still the best choice for transpositions following esophagectomy.

摘要

作者介绍了他们在1980年至1989年间对228例因食管癌和食管胃交界癌行食管切除术后进行食管成形术的经验。其中34例患者(24例食管胃成形术、8例食管十二指肠成形术、2例食管结肠成形术)接受了通过X线、测压、pH值测定和闪烁扫描进行的精确功能检查。特别是对食管胃成形术的研究表明,移植的器官缺乏运动活性,因此排空是靠重力实现的。还表明,碱性、酸性和混合型反流的程度与吻合口的位置有关:吻合口越靠近,受累程度越低。相反,对食管空肠成形术的研究突出了正常的运动功能:没有病例出现碱性反流。所研究的2例结肠成形术病例尽管测压未能检测到推进型运动波的存在,但排空有效。作者得出结论,尽管从功能角度来看空肠是最佳的移植替代器官,但其高度不一致且不稳定的血管化限制了该器官仅用于高位吻合。因此,作者认为,尽管胃倾向于表现为惰性管道,但仍是食管切除术后移植的最佳选择。

相似文献

1
[Functional study of intestinal transplants after esophagectomy].[食管癌切除术后肠道移植的功能研究]
Minerva Chir. 1991 Apr 15;46(7 Suppl):241-5.
2
[Functional evaluation of gastric and jejunal transplant after esophagectomy].[食管癌切除术后胃和空肠移植的功能评估]
Minerva Chir. 1991 Apr 15;46(7 Suppl):253-62.
3
[Functional evaluation of the intrathoracic stomach after esophagectomy for esophageal cancer].
Minerva Chir. 1991 Apr 15;46(7 Suppl):247-51.
4
The place of gastro-jejuno-duodenal interposition following limited esophageal resection.有限食管切除术后胃空肠十二指肠间置术的地位
Eur J Cardiothorac Surg. 2005 Aug;28(2):296-300. doi: 10.1016/j.ejcts.2005.04.039.
5
Short-segment intestinal interposition of the distal esophagus.食管远端短节段肠管间置术
J Thorac Cardiovasc Surg. 1993 Nov;106(5):860-6; discussion 866-7.
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Motor activity of esophageal substitute (stomach, jejunal, and colon segments).食管替代物(胃、空肠和结肠段)的运动活性。
Ann Thorac Surg. 1986 May;41(5):515-9. doi: 10.1016/s0003-4975(10)63031-7.
7
Reflux after esophagectomy and interposition of right colon.食管切除及右半结肠间置术后的反流
Can J Surg. 1994 Aug;37(4):289-92.
8
Postoperative functional result and quality of life after oesophageal reconstruction based on the type of cervical anastomosis.基于颈部吻合类型的食管重建术后功能结果及生活质量
Chirurgia (Bucur). 2015 Mar-Apr;110(2):109-16.
9
[Current views and controversies about reconstruction after esophagectomy].[关于食管癌切除术后重建的当前观点与争议]
G Chir. 1991 Mar;12(3):103-5.
10
[Manometric study of the esophagus and intrathoracic stomach after partial esophagectomy for carcinoma].[食管癌部分食管切除术后食管及胸内胃的测压研究]
Zhonghua Wai Ke Za Zhi. 1995 Mar;33(3):173-5.

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